| http://dbpedia.org/ontology/abstract
|
Les tubulina-tirosina carboxipeptidases (T … Les tubulina-tirosina carboxipeptidases (TCP) són un grup d'enzims que participen en el cicle de tirosinació/destirosinació de la tubulina. Aquest cicle consisteix en l'extracció de la tirosina C-terminal de l'α-tubulina per part de la TCP i la posterior re-addició d'aquesta tirosina per part de la tubulina-tirosina ligasa (TTL). Aquesta tirosinació/destirosinació és un senyal regulador important per a la mitosi, la fisiologia neuronal i per a la mecanotransducció muscular. Consegüentment, nivells anormals de la destirosinació reversible s’han relacionat amb càncer, cardiomiopaties i desorganització neuronal.ardiomiopaties i desorganització neuronal.
, Tubulinyl-Tyr carboxypeptidase (EC 3.4.17. … Tubulinyl-Tyr carboxypeptidase (EC 3.4.17.17, carboxypeptidase-tubulin, soluble carboxypeptidase, tubulin-tyrosine carboxypeptidase, tubulin carboxypeptidase, tubulinyltyrosine carboxypeptidase, tyrosinotubulin carboxypeptidase, tyrosyltubulin carboxypeptidase, TTCPase, brain I carboxypeptidase) is an enzyme. This enzyme catalyses the following chemical reaction Cleavage of the -Glu--Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr This enzyme is active at neutral pH. This activity has been linked to proteins such as in human. been linked to proteins such as in human.
|
| http://dbpedia.org/ontology/ecNumber
|
3.4.17.17
|
| http://dbpedia.org/ontology/wikiPageID
|
39264112
|
| http://dbpedia.org/ontology/wikiPageLength
|
2399
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
997218254
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Chemical_reaction +
, http://dbpedia.org/resource/Enzyme +
, http://dbpedia.org/resource/AGTPBP1 +
, http://dbpedia.org/resource/Tyrosine +
, http://dbpedia.org/resource/Tubulin +
, http://dbpedia.org/resource/Catalysis +
, http://dbpedia.org/resource/PH +
, http://dbpedia.org/resource/C-terminal +
, http://dbpedia.org/resource/Category:EC_3.4.17 +
, http://dbpedia.org/resource/Homo_sapiens +
|
| http://dbpedia.org/property/casNumber
|
73050
|
| http://dbpedia.org/property/ecNumber
|
3.4
|
| http://dbpedia.org/property/iubmbEcNumber
|
3
|
| http://dbpedia.org/property/name
|
Tubulinyl-Tyr carboxypeptidase
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:MeshName +
, http://dbpedia.org/resource/Template:Proteases +
, http://dbpedia.org/resource/Template:Infobox_enzyme +
, http://dbpedia.org/resource/Template:Portal_bar +
, http://dbpedia.org/resource/Template:Enzymes +
, http://dbpedia.org/resource/Template:EC_number +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:EC_3.4.17 +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Enzyme +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Tubulinyl-Tyr_carboxypeptidase?oldid=997218254&ns=0 +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Tubulinyl-Tyr_carboxypeptidase +
|
| http://xmlns.com/foaf/0.1/name
|
Tubulinyl-Tyr carboxypeptidase
|
| owl:sameAs |
http://sh.dbpedia.org/resource/Tubulinilna_Tyr_karboksipeptidaza +
, http://rdf.freebase.com/ns/m.0t_dprl +
, http://dbpedia.org/resource/Tubulinyl-Tyr_carboxypeptidase +
, http://www.wikidata.org/entity/Q12357539 +
, http://ca.dbpedia.org/resource/Tubulina_Carboxipeptidases_%28TCP%29 +
, http://sr.dbpedia.org/resource/Tubulinilna_Tyr_karboksipeptidaza +
, https://global.dbpedia.org/id/Gka9 +
|
| rdf:type |
http://dbpedia.org/ontology/Enzyme +
, http://dbpedia.org/class/yago/Catalyst114723628 +
, http://dbpedia.org/ontology/Protein +
, http://dbpedia.org/ontology/Biomolecule +
, http://dbpedia.org/class/yago/Matter100020827 +
, http://dbpedia.org/class/yago/Protein114728724 +
, http://dbpedia.org/class/yago/OrganicCompound114727670 +
, http://dbpedia.org/class/yago/Material114580897 +
, http://dbpedia.org/class/yago/Macromolecule114944888 +
, http://dbpedia.org/class/yago/Molecule114682133 +
, http://dbpedia.org/class/yago/Unit109465459 +
, http://dbpedia.org/class/yago/Compound114818238 +
, http://dbpedia.org/class/yago/Chemical114806838 +
, http://dbpedia.org/class/yago/Substance100019613 +
, http://dbpedia.org/class/yago/Thing100002452 +
, http://www.wikidata.org/entity/Q8047 +
, http://dbpedia.org/class/yago/Abstraction100002137 +
, http://dbpedia.org/class/yago/PhysicalEntity100001930 +
, http://dbpedia.org/class/yago/Relation100031921 +
, http://www.wikidata.org/entity/Q206229 +
, http://dbpedia.org/class/yago/Activator114723079 +
, http://dbpedia.org/class/yago/Enzyme114732946 +
, http://dbpedia.org/class/yago/Part113809207 +
|
| rdfs:comment |
Les tubulina-tirosina carboxipeptidases (T … Les tubulina-tirosina carboxipeptidases (TCP) són un grup d'enzims que participen en el cicle de tirosinació/destirosinació de la tubulina. Aquest cicle consisteix en l'extracció de la tirosina C-terminal de l'α-tubulina per part de la TCP i la posterior re-addició d'aquesta tirosina per part de la tubulina-tirosina ligasa (TTL). Aquesta tirosinació/destirosinació és un senyal regulador important per a la mitosi, la fisiologiar important per a la mitosi, la fisiologia
, Tubulinyl-Tyr carboxypeptidase (EC 3.4.17. … Tubulinyl-Tyr carboxypeptidase (EC 3.4.17.17, carboxypeptidase-tubulin, soluble carboxypeptidase, tubulin-tyrosine carboxypeptidase, tubulin carboxypeptidase, tubulinyltyrosine carboxypeptidase, tyrosinotubulin carboxypeptidase, tyrosyltubulin carboxypeptidase, TTCPase, brain I carboxypeptidase) is an enzyme. This enzyme catalyses the following chemical reaction Cleavage of the -Glu--Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr This enzyme is active at neutral pH. This activity has been linked to proteins such as in human. been linked to proteins such as in human.
|
| rdfs:label |
Tubulinyl-Tyr carboxypeptidase
, Tubulina Carboxipeptidases (TCP)
|
