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, Ravuconazol é um fármaco antifúngico triaz … Ravuconazol é um fármaco antifúngico triazólico desenvolvido pela Bristol-Myers Squibb, que está em fase de testes clínicos. A droga tem demonstrado um espectro de ação similar ao voriconazol, com uma meia-vida biológica aumentada. Entretanto, o ravuconazol tem uma limitada ação contra espécies dos gêneros Fusarium, e Zygomycetes. O ravuconazol possui atividade anti-Trypanosoma in vivo e in vitro, e devido a meia-vida plasmática elevada (4 a 8 dias) em humanos faz dele uma droga promissora para ser usada no tratamento da doença de Chagas.r usada no tratamento da doença de Chagas.
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| rdfs:comment |
Ravuconazole (codenamed BMS-207147 and ER- … Ravuconazole (codenamed BMS-207147 and ER-30346) is a potent triazole antifungal, the development of which was discontinued in 2007. The drug has shown to have a similar spectrum of activity to voriconazole, with an increased half-life. However, ravuconazole has limited activity against species of Fusarium, Scedosporium, and Zygomycetes.f Fusarium, Scedosporium, and Zygomycetes.
, Ravuconazol é um fármaco antifúngico triaz … Ravuconazol é um fármaco antifúngico triazólico desenvolvido pela Bristol-Myers Squibb, que está em fase de testes clínicos. A droga tem demonstrado um espectro de ação similar ao voriconazol, com uma meia-vida biológica aumentada. Entretanto, o ravuconazol tem uma limitada ação contra espécies dos gêneros Fusarium, e Zygomycetes. O ravuconazol possui atividade anti-Trypanosoma in vivo e in vitro, e devido a meia-vida plasmática elevada (4 a 8 dias) em humanos faz dele uma droga promissora para ser usada no tratamento da doença de Chagas.r usada no tratamento da doença de Chagas.
|
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Ravuconazol
, Ravuconazole
|
