| http://dbpedia.org/ontology/abstract
|
DEPBT (3-(diethoxyphosphoryloxy)-1,2,3-ben … DEPBT (3-(diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one) is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization. Fmoc-Dab(Mtt)-OH, a commercially available amino acid building block for solid-phase peptide synthesis (SPPS), was proven to undergo rapid lactamization, instead of reacting with the N-terminal end of the peptide. Compared with other commercially available coupling reagents, DEPBT has shown superior performance in coupling Fmoc-Dab(Mtt)-OH to the N-terminal end of peptide during SPPS, though the approach was regarded as 'costly and tedious'.oach was regarded as 'costly and tedious'.
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| http://dbpedia.org/ontology/alternativeName
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DEPBT
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| http://dbpedia.org/ontology/iupacName
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Diethyl 4-oxo-1,2,3-benzotriazin-3(4H)-yl phosphate
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| http://dbpedia.org/ontology/thumbnail
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http://commons.wikimedia.org/wiki/Special:FilePath/DEPBT.svg?width=300 +
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| http://dbpedia.org/ontology/wikiPageID
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45545331
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| http://dbpedia.org/ontology/wikiPageLength
|
1722
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| http://dbpedia.org/ontology/wikiPageRevisionID
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1105954608
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| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/PyBOP +
, http://dbpedia.org/resource/Peptide_synthesis +
, http://dbpedia.org/resource/Racemization +
, http://dbpedia.org/resource/Category:Biochemistry +
, http://dbpedia.org/resource/Coupling_reaction +
, http://dbpedia.org/resource/Reagent +
, http://dbpedia.org/resource/Category:Reagents_for_biochemistry +
, http://dbpedia.org/resource/Peptide +
, http://dbpedia.org/resource/Category:Peptide_coupling_reagents +
, http://dbpedia.org/resource/Category:Biochemistry_methods +
, http://dbpedia.org/resource/Category:Organophosphates +
, http://dbpedia.org/resource/BOP_reagent +
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| http://dbpedia.org/property/imagefile
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DEPBT ball.png
, DEPBT.svg
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| http://dbpedia.org/property/othernames
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DEPBT
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| http://dbpedia.org/property/pin
|
Diethyl 4-oxo-1,2,3-benzotriazin-3-yl phosphate
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| http://dbpedia.org/property/verifiedfields
|
changed
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changed
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http://dbpedia.org/resource/Template:Organic-compound-stub +
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| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Peptide_coupling_reagents +
, http://dbpedia.org/resource/Category:Biochemistry +
, http://dbpedia.org/resource/Category:Organophosphates +
, http://dbpedia.org/resource/Category:Reagents_for_biochemistry +
, http://dbpedia.org/resource/Category:Biochemistry_methods +
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| http://purl.org/linguistics/gold/hypernym
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http://dbpedia.org/resource/Reagent +
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| http://www.w3.org/ns/prov#wasDerivedFrom
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http://en.wikipedia.org/wiki/DEPBT?oldid=1105954608&ns=0 +
|
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|
http://commons.wikimedia.org/wiki/Special:FilePath/DEPBT.svg +
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|
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|
http://en.wikipedia.org/wiki/DEPBT +
|
| owl:sameAs |
http://dbpedia.org/resource/DEPBT +
, http://www.wikidata.org/entity/Q19596789 +
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, http://yago-knowledge.org/resource/DEPBT +
, https://global.dbpedia.org/id/rzCf +
|
| rdf:type |
http://dbpedia.org/ontology/ChemicalCompound +
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|
| rdfs:comment |
DEPBT (3-(diethoxyphosphoryloxy)-1,2,3-ben … DEPBT (3-(diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one) is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization. Fmoc-Dab(Mtt)-OH, a commercially available amino acid building block for solid-phase peptide synthesis (SPPS), was proven to undergo rapid lactamization, instead of reacting with the N-terminal end of the peptide. Compared with other commercially available coupling reagents, DEPBT has shown superior performance in coupling Fmoc-Dab(Mtt)-OH to the N-terminal end of peptide during SPPS, though the approach was regarded as 'costly and tedious'.oach was regarded as 'costly and tedious'.
|
| rdfs:label |
DEPBT
|
