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Zaurategrast (CDP323) ist ein experimentel … Zaurategrast (CDP323) ist ein experimenteller Arzneistoff, der auf seine Eignung zur Behandlung der multiplen Sklerose (MS) untersucht wurde. Es handelt sich um einen α4-Integrin-Hemmer. Zaurategrast ist ein kleines chemisches Molekül, das als prodrug zum Einsatz kommt.olekül, das als prodrug zum Einsatz kommt.
, Zaurategrast (CDP323) is a small-molecule … Zaurategrast (CDP323) is a small-molecule prodrug antagonist of the vascular cell adhesion molecule 1 (VCAM-1) binding to α4-integrins. It was originally developed by the British biopharmaceutical company Celltech plc. (now UCB S.A.) and was a putative new drug for oral treatment of multiple sclerosis. In October 2006, UCB and Biogen Idec announced a collaboration to jointly develop and commercialize zaurategrast for the treatment of multiple sclerosis and other potential indications. In June 2009, development of zaurategrast was discontinued due to discouraging results of a Phase II clinical trial.ging results of a Phase II clinical trial.
, CDP323 is een kleine molecule die onderzocht werd als therapie voor multiple sclerose. Het was in ontwikkeling door UCB en had de eerste orale M.S.-remmer kunnen worden.
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rdfs:comment |
Zaurategrast (CDP323) ist ein experimentel … Zaurategrast (CDP323) ist ein experimenteller Arzneistoff, der auf seine Eignung zur Behandlung der multiplen Sklerose (MS) untersucht wurde. Es handelt sich um einen α4-Integrin-Hemmer. Zaurategrast ist ein kleines chemisches Molekül, das als prodrug zum Einsatz kommt.olekül, das als prodrug zum Einsatz kommt.
, Zaurategrast (CDP323) is a small-molecule … Zaurategrast (CDP323) is a small-molecule prodrug antagonist of the vascular cell adhesion molecule 1 (VCAM-1) binding to α4-integrins. It was originally developed by the British biopharmaceutical company Celltech plc. (now UCB S.A.) and was a putative new drug for oral treatment of multiple sclerosis. for oral treatment of multiple sclerosis.
, CDP323 is een kleine molecule die onderzocht werd als therapie voor multiple sclerose. Het was in ontwikkeling door UCB en had de eerste orale M.S.-remmer kunnen worden.
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rdfs:label |
Zaurategrast
, CDP323
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