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ビリジン(Viridin)は、Gliocladium virensの抗菌性代謝物で、1945年に初めて報告された。の1つで、求電子のがC-4位とC-6位の間でステロイド骨格に融合した構造を持つ。を含むビリジン類は、PI3キナーゼの不可逆的共有結合阻害剤になりうることが知られている。
, Viridin is an antifungal metabolite of Gli … Viridin is an antifungal metabolite of Gliocladium virens that was first reported in 1945. Belonging to a class of molecules known as furanosteroids, it has a characteristic highly strained electrophilic furan ring fused between C-4 and C-6 of the steroid framework. Members of this family, including wortmannin, are known to be potent, irreversible covalent inhibitors of phosphoinositide 3-kinases (PI3Ks).ors of phosphoinositide 3-kinases (PI3Ks).
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| rdfs:comment |
Viridin is an antifungal metabolite of Gli … Viridin is an antifungal metabolite of Gliocladium virens that was first reported in 1945. Belonging to a class of molecules known as furanosteroids, it has a characteristic highly strained electrophilic furan ring fused between C-4 and C-6 of the steroid framework. Members of this family, including wortmannin, are known to be potent, irreversible covalent inhibitors of phosphoinositide 3-kinases (PI3Ks).ors of phosphoinositide 3-kinases (PI3Ks).
, ビリジン(Viridin)は、Gliocladium virensの抗菌性代謝物で、1945年に初めて報告された。の1つで、求電子のがC-4位とC-6位の間でステロイド骨格に融合した構造を持つ。を含むビリジン類は、PI3キナーゼの不可逆的共有結合阻害剤になりうることが知られている。
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| rdfs:label |
ビリジン
, Viridin
|
