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タネスピマイシン(Tanespimycin)は、癌、特に若い患者の白血病や腎臓腫瘍の治療の研究が行われているの誘導体である。 これらの腫瘍で発現するHsp90を阻害することにより、作用する。 抗腫瘍抗生物質に分類される。
, La tanespimycine, ou 17-(allylamino)-17-dé … La tanespimycine, ou 17-(allylamino)-17-déméthoxygeldanamycine (17-AAG), est un antibiotique dérivé de la geldanamycine qui a été étudié pour le traitement de cancers, spécifiquement chez les patients jeunes atteints de certains types de leucémie et tumeurs des reins. Elle fonctionne comme inhibiteur de la protéine Hsp90, exprimée dans ces cancers.protéine Hsp90, exprimée dans ces cancers.
, Tanespimycin (17-N-allylamino-17-demethoxy … Tanespimycin (17-N-allylamino-17-demethoxygeldanamycin, 17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specifically in younger patients with certain types of leukemia or solid tumors, especially kidney tumors. It works by inhibiting Hsp90, which is expressed in those tumors. It belongs to the family of drugs called antitumor antibiotics.ily of drugs called antitumor antibiotics.
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, 17-AAG
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[(3S,5S,6R,7S,8E,10R,11S,12E,14E)-21-(allylamino)-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-8,12,14,18,21-pentaen-10-yl] carbamate
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| rdfs:comment |
Tanespimycin (17-N-allylamino-17-demethoxy … Tanespimycin (17-N-allylamino-17-demethoxygeldanamycin, 17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specifically in younger patients with certain types of leukemia or solid tumors, especially kidney tumors. It works by inhibiting Hsp90, which is expressed in those tumors. It belongs to the family of drugs called antitumor antibiotics.ily of drugs called antitumor antibiotics.
, La tanespimycine, ou 17-(allylamino)-17-dé … La tanespimycine, ou 17-(allylamino)-17-déméthoxygeldanamycine (17-AAG), est un antibiotique dérivé de la geldanamycine qui a été étudié pour le traitement de cancers, spécifiquement chez les patients jeunes atteints de certains types de leucémie et tumeurs des reins. Elle fonctionne comme inhibiteur de la protéine Hsp90, exprimée dans ces cancers.protéine Hsp90, exprimée dans ces cancers.
, タネスピマイシン(Tanespimycin)は、癌、特に若い患者の白血病や腎臓腫瘍の治療の研究が行われているの誘導体である。 これらの腫瘍で発現するHsp90を阻害することにより、作用する。 抗腫瘍抗生物質に分類される。
|
| rdfs:label |
タネスピマイシン
, Tanespimycin
, Tanespimycine
|
