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Une sphingosine kinase (SphK) est une enzy … Une sphingosine kinase (SphK) est une enzyme (en l'occurrence une kinase) qui catalyse la conversion de la sphingosine en sphingosine-1-phosphate (S1P : un sphingolipide de signalisation cellulaire, qui agit comme un médiateur lipidique bioactif) par phosphorylation (addition d'un groupe phosphoryle —PO32−). Dans la nomenclature EC, les sphingosine kinases portent la référence EC 2.7.1.91. kinases portent la référence EC 2.7.1.91.
, Sphingosine kinase (SphK) is a conserved l … Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine. Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate, are lipid second messengers involved in diverse cellular processes. There are two forms of SphK, SphK1 and SphK2. SphK1 is found in the cytosol of eukaryotic cells, and migrates to the plasma membrane upon activation. SphK2 is localized to the nucleus.vation. SphK2 is localized to the nucleus.
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| rdfs:comment |
Une sphingosine kinase (SphK) est une enzy … Une sphingosine kinase (SphK) est une enzyme (en l'occurrence une kinase) qui catalyse la conversion de la sphingosine en sphingosine-1-phosphate (S1P : un sphingolipide de signalisation cellulaire, qui agit comme un médiateur lipidique bioactif) par phosphorylation (addition d'un groupe phosphoryle —PO32−). Dans la nomenclature EC, les sphingosine kinases portent la référence EC 2.7.1.91. kinases portent la référence EC 2.7.1.91.
, Sphingosine kinase (SphK) is a conserved l … Sphingosine kinase (SphK) is a conserved lipid kinase that catalyzes formation sphingosine-1-phosphate (S1P) from the precursor sphingolipid sphingosine. Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate, are lipid second messengers involved in diverse cellular processes. There are two forms of SphK, SphK1 and SphK2. SphK1 is found in the cytosol of eukaryotic cells, and migrates to the plasma membrane upon activation. SphK2 is localized to the nucleus.vation. SphK2 is localized to the nucleus.
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Sphingosine kinase
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