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Ro 3-0419 is a highly toxic organophosphat … Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It is the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice.nous LD50 of Ro 3-0419 is 1 mg/kg in mice.
|
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|
3-(Diethoxyphosphinyloxy)-quinoline
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|
Diethyl quinolin-3-yl phosphate
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1673
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Ro 3-0419
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3
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Diethyl quinolin-3-yl phosphate
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| rdfs:comment |
Ro 3-0419 is a highly toxic organophosphat … Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It is the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice.nous LD50 of Ro 3-0419 is 1 mg/kg in mice.
|
| rdfs:label |
Ro 3-0419
|
