| http://dbpedia.org/ontology/abstract
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RNA silencing suppressor p19 (also known a … RNA silencing suppressor p19 (also known as Tombusvirus P19 core protein and 19 kDa symptom severity modulator) is a protein expressed from the ORF4 gene in the genome of tombusviruses. These viruses are positive-sense single-stranded RNA viruses that infect plant cells, in which RNA silencing forms a widespread and robust antiviral defense system. The p19 protein serves as a counter-defense strategy, specifically binding the 19- to 21-nucleotide double-stranded RNAs that function as small interfering RNA (siRNA) in the RNA silencing system. By sequestering siRNA, p19 suppresses RNA silencing and promotes viral proliferation. The p19 protein is considered a significant virulence factor and a component of an evolutionary arms race between plants and their pathogens.s race between plants and their pathogens.
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Tombus_p19
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http://commons.wikimedia.org/wiki/Special:FilePath/1R9F_tombusvirus_p19_dimer.png?width=300 +
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52500756
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11022
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1032089947
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| http://dbpedia.org/property/caption
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The protein dimer formed by two p19 molecules. Each monomer is colored from N-terminus to C-terminus to illustrate the end-to-end orientation of the dimer. The dotted gray line in the center highlights the dimer interface. From .
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| http://dbpedia.org/property/interpro
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IPR004905
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| http://dbpedia.org/property/name
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RNA silencing suppressor p19
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| http://dbpedia.org/property/pfam
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PF03220
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| http://dbpedia.org/property/symbol
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Tombus_p19
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http://en.wikipedia.org/wiki/RNA_silencing_suppressor_p19?oldid=1032089947&ns=0 +
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http://commons.wikimedia.org/wiki/Special:FilePath/1R9F_tombusvirus_p19.png +
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|
| rdfs:comment |
RNA silencing suppressor p19 (also known a … RNA silencing suppressor p19 (also known as Tombusvirus P19 core protein and 19 kDa symptom severity modulator) is a protein expressed from the ORF4 gene in the genome of tombusviruses. These viruses are positive-sense single-stranded RNA viruses that infect plant cells, in which RNA silencing forms a widespread and robust antiviral defense system. The p19 protein serves as a counter-defense strategy, specifically binding the 19- to 21-nucleotide double-stranded RNAs that function as small interfering RNA (siRNA) in the RNA silencing system. By sequestering siRNA, p19 suppresses RNA silencing and promotes viral proliferation. The p19 protein is considered a significant virulence factor and a component of an evolutionary arms race between plants and their pathogens.s race between plants and their pathogens.
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| rdfs:label |
RNA silencing suppressor p19
|
