| http://dbpedia.org/ontology/abstract
|
Quinolidomicin A1 is a 60-membered macrocy … Quinolidomicin A1 is a 60-membered macrocyclic compound isolated from Micromonospora sp. JY16. are a class of macrolides that contain a benzoquinone chromophore as well as an immense lactone ring, which far surpasses that in . It is currently the largest identified macrolide of terrestrial origin. It was initially discovered when in a screening for anti-tumor antibiotics, where it was found to be cytotoxic against P388 murine leukemia cells (IC50 8 nM), and has later been found to have strong cytotoxic activity against HT-29, MKN28, K562, and KB.tivity against HT-29, MKN28, K562, and KB.
|
| http://dbpedia.org/ontology/iupacName
|
(21Z,23Z,25Z,33Z,35Z,50Z,52Z)-1,7,9,17,19, … (21Z,23Z,25Z,33Z,35Z,50Z,52Z)-1,7,9,17,19,27,31,37,39,41,45,47,49,55,59-pentadecahydroxy-5-[(1E,3E)-8-(5-hydroxy-2-methylsulfanyl-3,6-dioxocyclohexa-1,4-dien-1-yl)-8-methoxy-5-methylocta-1,3-dienyl]-14,44,48,50,54,56,58-heptamethyl-4,61-dioxabicyclo[55.3.1]henhexaconta-21,23,25,33,35,50,52-heptaene-3,29-dionea-21,23,25,33,35,50,52-heptaene-3,29-dione
|
| rdfs:comment |
Quinolidomicin A1 is a 60-membered macrocy … Quinolidomicin A1 is a 60-membered macrocyclic compound isolated from Micromonospora sp. JY16. are a class of macrolides that contain a benzoquinone chromophore as well as an immense lactone ring, which far surpasses that in . It is currently the largest identified macrolide of terrestrial origin. It was initially discovered when in a screening for anti-tumor antibiotics, where it was found to be cytotoxic against P388 murine leukemia cells (IC50 8 nM), and has later been found to have strong cytotoxic activity against HT-29, MKN28, K562, and KB.tivity against HT-29, MKN28, K562, and KB.
|
