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Il PWZ-029 è uno psicofarmaco appartenente … Il PWZ-029 è uno psicofarmaco appartenente alla categoria delle che con effetti nootropici sviluppato da WiSys; agisce come un sottotipo selettivo, misto agonista inverso del recettore GABA A, agendo come agonista inverso parziale a livello del sottotipo α5 e un debole agonista parziale al sottotipo α3. Questo gli conferisce un profilo farmacologico misto, producendo a basse dosi effetti di miglioramento della memoria ma senza convulsioni o effetti ansiogeni o debolezza muscolare, sebbene a dosi più elevate produca alcuni effetti sedativi.ù elevate produca alcuni effetti sedativi.
, PWZ-029 is a benzodiazepine derivative dru … PWZ-029 is a benzodiazepine derivative drug with nootropic effects developed by WiSys, It acts as a subtype-selective, mixed agonist-inverse agonist at the benzodiazepine binding site on the GABAA receptor, acting as a partial inverse agonist at the α5 subtype and a weak partial agonist at the α3 subtype. This gives it a mixed pharmacological profile, producing at low doses memory-enhancing effects but with no convulsant or anxiogenic effects or muscle weakness, although at higher doses it produces some sedative effects.r doses it produces some sedative effects.
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| rdfs:comment |
PWZ-029 is a benzodiazepine derivative dru … PWZ-029 is a benzodiazepine derivative drug with nootropic effects developed by WiSys, It acts as a subtype-selective, mixed agonist-inverse agonist at the benzodiazepine binding site on the GABAA receptor, acting as a partial inverse agonist at the α5 subtype and a weak partial agonist at the α3 subtype. This gives it a mixed pharmacological profile, producing at low doses memory-enhancing effects but with no convulsant or anxiogenic effects or muscle weakness, although at higher doses it produces some sedative effects.r doses it produces some sedative effects.
, Il PWZ-029 è uno psicofarmaco appartenente … Il PWZ-029 è uno psicofarmaco appartenente alla categoria delle che con effetti nootropici sviluppato da WiSys; agisce come un sottotipo selettivo, misto agonista inverso del recettore GABA A, agendo come agonista inverso parziale a livello del sottotipo α5 e un debole agonista parziale al sottotipo α3. Questo gli conferisce un profilo farmacologico misto, producendo a basse dosi effetti di miglioramento della memoria ma senza convulsioni o effetti ansiogeni o debolezza muscolare, sebbene a dosi più elevate produca alcuni effetti sedativi.ù elevate produca alcuni effetti sedativi.
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| rdfs:label |
PWZ-029
|
