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http://dbpedia.org/ontology/abstract Oncogene addiction is a process in which cOncogene addiction is a process in which cancers with genetic, epigenetic, or chromosomal irregularities become dependent on one or several genes for maintenance and survival. As a result, cancer cells rely on continuous signaling from these oncogenes for their survival. The term was coined in 2002 by American physician I. Bernard Weinstein.y American physician I. Bernard Weinstein. , En cancérologie, l'addiction oncogénique, En cancérologie, l'addiction oncogénique, ou mutation oncogénique, est un phénomène survenant lorsque la survie d'une cellule cancéreuse est totalement dépendante de l'activation continuelle d'une voie de signalisation cellulaire. L'inactivation de cette voie de signalisation entraîne alors la mort cellulaire par apoptose. Ceci est le mode d'action de certaines thérapies ciblées.e d'action de certaines thérapies ciblées.
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rdfs:comment En cancérologie, l'addiction oncogénique, En cancérologie, l'addiction oncogénique, ou mutation oncogénique, est un phénomène survenant lorsque la survie d'une cellule cancéreuse est totalement dépendante de l'activation continuelle d'une voie de signalisation cellulaire. L'inactivation de cette voie de signalisation entraîne alors la mort cellulaire par apoptose. Ceci est le mode d'action de certaines thérapies ciblées.e d'action de certaines thérapies ciblées. , Oncogene addiction is a process in which cOncogene addiction is a process in which cancers with genetic, epigenetic, or chromosomal irregularities become dependent on one or several genes for maintenance and survival. As a result, cancer cells rely on continuous signaling from these oncogenes for their survival. The term was coined in 2002 by American physician I. Bernard Weinstein.y American physician I. Bernard Weinstein.
rdfs:label Addiction oncogénique , Oncogene addiction
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