| http://dbpedia.org/ontology/abstract
|
omega-Atracotoxin (ω-atracotoxin) is an in … omega-Atracotoxin (ω-atracotoxin) is an insect-specific neurotoxin produced by the Blue Mountains funnel-web spider. Its phylogenetic specificity derives from its ability to antagonise insect, but not vertebrate, voltage-gated calcium channels. Two spatially proximal amino acid residues, Asn(27) and Arg(35), form a contiguous molecular surface that is essential for toxin activity. It has been proposed that this surface of the beta-hairpin is a key site for interaction of the toxin with insect calcium channels.of the toxin with insect calcium channels.
|
| http://dbpedia.org/ontology/symbol
|
Omega-toxin
|
| http://dbpedia.org/ontology/wikiPageID
|
31911373
|
| http://dbpedia.org/ontology/wikiPageLength
|
1474
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
950946437
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Category:Neurotoxins +
, http://dbpedia.org/resource/Voltage-gated_calcium_channel +
, http://dbpedia.org/resource/Category:Ion_channel_toxins +
, http://dbpedia.org/resource/Category:Protein_toxins +
, http://dbpedia.org/resource/Hadronyche_versuta +
, http://dbpedia.org/resource/Atracotoxin +
, http://dbpedia.org/resource/Neurotoxin +
, http://dbpedia.org/resource/Beta-hairpin +
, http://dbpedia.org/resource/Amino_acid +
|
| http://dbpedia.org/property/interpro
|
IPR009415
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| http://dbpedia.org/property/name
|
ω-Atracotoxin
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| http://dbpedia.org/property/pdb
|
A:4-23 :1-37
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| http://dbpedia.org/property/pfam
|
PF06357
|
| http://dbpedia.org/property/scop
|
1
|
| http://dbpedia.org/property/symbol
|
Omega-toxin
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Neurotoxin-stub +
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, http://dbpedia.org/resource/Template:PDB3 +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Neurotoxins +
, http://dbpedia.org/resource/Category:Protein_toxins +
, http://dbpedia.org/resource/Category:Ion_channel_toxins +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Omega-Atracotoxin?oldid=950946437&ns=0 +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Omega-Atracotoxin +
|
| owl:sameAs |
http://dbpedia.org/resource/Omega-Atracotoxin +
, http://www.wikidata.org/entity/Q24773966 +
, https://global.dbpedia.org/id/2L6MX +
|
| rdf:type |
http://www.wikidata.org/entity/Q206229 +
, http://www.wikidata.org/entity/Q8054 +
, http://dbpedia.org/ontology/Protein +
, http://dbpedia.org/ontology/Biomolecule +
|
| rdfs:comment |
omega-Atracotoxin (ω-atracotoxin) is an in … omega-Atracotoxin (ω-atracotoxin) is an insect-specific neurotoxin produced by the Blue Mountains funnel-web spider. Its phylogenetic specificity derives from its ability to antagonise insect, but not vertebrate, voltage-gated calcium channels. Two spatially proximal amino acid residues, Asn(27) and Arg(35), form a contiguous molecular surface that is essential for toxin activity. It has been proposed that this surface of the beta-hairpin is a key site for interaction of the toxin with insect calcium channels.of the toxin with insect calcium channels.
|
| rdfs:label |
Omega-Atracotoxin
|
