| http://dbpedia.org/ontology/abstract
|
NMP-7 is a drug which acts as both a non-s … NMP-7 is a drug which acts as both a non-selective agonist of the CB1 and CB2 cannabinoid receptors, and also as a blocker of T-type calcium channels, the target of anticonvulsant drugs such as ethosuximide. NMP-7 has an agonist EC50 of 96.9nM at CB1 and 10.5nM at CB2, and an IC50 of 1.84μM for blocking Cav3.2 T-type calcium channels. In animal studies it produces potent analgesic effects in a variety of different tests.c effects in a variety of different tests.
|
| http://dbpedia.org/ontology/casNumber
|
1358039-07-2
|
| http://dbpedia.org/ontology/pubchem
|
46871949
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/NMP-7_structure.png?width=300 +
|
| http://dbpedia.org/ontology/wikiPageID
|
35588417
|
| http://dbpedia.org/ontology/wikiPageLength
|
1763
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1082425031
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Analgesic +
, http://dbpedia.org/resource/Category:Cannabinoids +
, http://dbpedia.org/resource/Anticonvulsant +
, http://dbpedia.org/resource/EG-018 +
, http://dbpedia.org/resource/Agonist +
, http://dbpedia.org/resource/Ethosuximide +
, http://dbpedia.org/resource/Category:Carbazoles +
, http://dbpedia.org/resource/Cannabinoid_receptor +
, http://dbpedia.org/resource/T-type_calcium_channel +
, http://dbpedia.org/resource/CUMYL-PEGACLONE +
, http://dbpedia.org/resource/Cannabinoid_receptor_2 +
, http://dbpedia.org/resource/Cannabinoid_receptor_1 +
|
| http://dbpedia.org/property/c
|
23
|
| http://dbpedia.org/property/casNumber
|
1358039
|
| http://dbpedia.org/property/chemspiderid
|
27470961
|
| http://dbpedia.org/property/h
|
28
|
| http://dbpedia.org/property/iupacName
|
-piperidin-1-ylmethanone
|
| http://dbpedia.org/property/n
|
2
|
| http://dbpedia.org/property/o
|
1
|
| http://dbpedia.org/property/pubchem
|
46871949
|
| http://dbpedia.org/property/smiles
|
c3cccc1c3ncc1cc2CN4CCCCC4
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
NZEVKZAEMSMLMC-UHFFFAOYSA-N
|
| http://dbpedia.org/property/width
|
200
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Cannabinoid-stub +
, http://dbpedia.org/resource/Template:Cannabinoids +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Short_description +
, http://dbpedia.org/resource/Template:Drugbox +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Carbazoles +
, http://dbpedia.org/resource/Category:Cannabinoids +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Drug +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/NMP-7?oldid=1082425031&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/NMP-7_structure.png +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/NMP-7 +
|
| owl:sameAs |
http://rdf.freebase.com/ns/m.0jkwhkb +
, http://dbpedia.org/resource/NMP-7 +
, https://global.dbpedia.org/id/4rgmA +
, http://sr.dbpedia.org/resource/NMP-7 +
, http://www.wikidata.org/entity/Q6954747 +
, http://sh.dbpedia.org/resource/NMP-7 +
|
| rdf:type |
http://dbpedia.org/ontology/Drug +
, http://www.wikidata.org/entity/Q8386 +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
, http://dbpedia.org/ontology/ChemicalSubstance +
|
| rdfs:comment |
NMP-7 is a drug which acts as both a non-s … NMP-7 is a drug which acts as both a non-selective agonist of the CB1 and CB2 cannabinoid receptors, and also as a blocker of T-type calcium channels, the target of anticonvulsant drugs such as ethosuximide. NMP-7 has an agonist EC50 of 96.9nM at CB1 and 10.5nM at CB2, and an IC50 of 1.84μM for blocking Cav3.2 T-type calcium channels. In animal studies it produces potent analgesic effects in a variety of different tests.c effects in a variety of different tests.
|
| rdfs:label |
NMP-7
|
