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The miR-129 microRNA precursor is a small … The miR-129 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. This microRNA was first experimentally characterised in mouse and homologues have since been discovered in several other species, such as humans, rats and zebrafish. The mature sequence is excised by the Dicer enzyme from the 5' arm of the hairpin. It was elucidated by Calin et al. that miR-129-1 is located in a fragile site region of the human genome near a specific site, FRA7H in chromosome 7q32, which is a site commonly deleted in many cancers. miR-129-2 is located in 11p11.2. cancers. miR-129-2 is located in 11p11.2.
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https://www.ncbi.nlm.nih.gov/gene/406917 +
, https://www.ncbi.nlm.nih.gov/gene/406918 +
, https://archive.today/20121223054724/http:/microrna.sanger.ac.uk/cgi-bin/sequences/mirna_summary.pl%3Ffam=MIPF0000073 +
, https://web.archive.org/web/20101015061512/http:/www.ebi.ac.uk/gxa/gene/MIMAT0000242 +
, https://semanticscholar.org/paper/06f8bc946e1d375bc780069f4ab5e8fcbf400783 +
, http://mirdb.org/cgi-bin/search.cgi%3FsearchType=miRNA&searchBox=hsa-miR-129-3p&full=1 +
, http://mirdb.org/cgi-bin/search.cgi%3FsearchType=miRNA&searchBox=hsa-miR-129-5p&full=1 +
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Predicted secondary structure and sequence conservation of mir-129
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miR-129 microRNA precursor family
, mir-129 microRNA precursor family
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The miR-129 microRNA precursor is a small … The miR-129 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. This microRNA was first experimentally characterised in mouse and homologues have since been discovered in several other species, such as humans, rats and zebrafish. The mature sequence is excised by the Dicer enzyme from the 5' arm of the hairpin. It was elucidated by Calin et al. that miR-129-1 is located in a fragile site region of the human genome near a specific site, FRA7H in chromosome 7q32, which is a site commonly deleted in many cancers. miR-129-2 is located in 11p11.2. cancers. miR-129-2 is located in 11p11.2.
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Mir-129 microRNA precursor family
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