| http://dbpedia.org/ontology/abstract
|
Mestranol ist ein synthetischer Arzneistoff aus der Gruppe der Estrogene. Es ist ein Prodrug (eine inaktive Vorstufe) des häufig in Arzneimitteln zur Empfängnisverhütung eingesetzten Ethinylestradiols.
, Mestranol, sold under the brand names Enov … Mestranol, sold under the brand names Enovid, Norinyl, and Ortho-Novum among others, is an estrogen medication which has been used in birth control pills, menopausal hormone therapy, and the treatment of menstrual disorders. It is formulated in combination with a progestin and is not available alone. It is taken by mouth. Side effects of mestranol include nausea, breast tension, edema, and breakthrough bleeding among others. It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. Mestranol is a prodrug of ethinylestradiol in the body. Mestranol was discovered in 1956 and was introduced for medical use in 1957. It was the estrogen component in the first birth control pill. In 1969, mestranol was replaced by ethinylestradiol in most birth control pills, although mestranol continues to be used in a few birth control pills even today. Mestranol remains available only in a few countries, including the United States, United Kingdom, Japan, and Chile. States, United Kingdom, Japan, and Chile.
, O mestranol (DCI; nomes de marca: Devocin, … O mestranol (DCI; nomes de marca: Devocin, Ovastol, Tranel, entre outros; também conhecido como etinilestradiol 3-metil éter, EEME, EE3ME) é um estrogênio esteroide sintético amplamente utilizado para fins contraceptivos. Foi empregado como o componente do estrogênico em muitos dos primeiros contraceptivos orais, tais como o mestranol / noretynodrel (nomes de tipo Enovid, Enavid), e é usado ainda hoje. Foi também um componente de Ortho-Novum, Ortho-Novin, Femigen, e Norbiogest. Além do seu uso como contraceptivo oral, o mestranol tem sido usado como um componente da terapia de reposição hormonal.mponente da terapia de reposição hormonal.
|
| http://dbpedia.org/ontology/alternativeName
|
Enovid, Norinyl, Ortho-Novum, others
|
| http://dbpedia.org/ontology/casNumber
|
72-33-3
|
| http://dbpedia.org/ontology/chEBI
|
6784
|
| http://dbpedia.org/ontology/chEMBL
|
1201151
|
| http://dbpedia.org/ontology/class
|
http://dbpedia.org/resource/Estrogen_ether +
, http://dbpedia.org/resource/Estrogen_%28medication%29 +
|
| http://dbpedia.org/ontology/drugbank
|
DB01357
|
| http://dbpedia.org/ontology/fdaUniiCode
|
B2V233XGE7
|
| http://dbpedia.org/ontology/kegg
|
D00575
|
| http://dbpedia.org/ontology/medlinePlus
|
a601050
|
| http://dbpedia.org/ontology/pubchem
|
6291
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/Mestranol.svg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageID
|
7721911
|
| http://dbpedia.org/ontology/wikiPageLength
|
21992
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1123032923
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/In_vitro +
, http://dbpedia.org/resource/Symptom +
, http://dbpedia.org/resource/Category:Prodrugs +
, http://dbpedia.org/resource/Noretynodrel +
, http://dbpedia.org/resource/Generic_term +
, http://dbpedia.org/resource/Venous_thromboembolism +
, http://dbpedia.org/resource/Testicular_size +
, http://dbpedia.org/resource/Menstrual_disorder +
, http://dbpedia.org/resource/Estrogen_receptor +
, http://dbpedia.org/resource/Demethylation +
, http://dbpedia.org/resource/California +
, http://dbpedia.org/resource/Gynecomastia +
, http://dbpedia.org/resource/Menopause +
, http://dbpedia.org/resource/Category:Ethynyl_compounds +
, http://dbpedia.org/resource/Prodrug +
, http://dbpedia.org/resource/Side_effect +
, http://dbpedia.org/resource/Puerto_Rico +
, http://dbpedia.org/resource/Clinical_trial +
, http://dbpedia.org/resource/Estradiol +
, http://dbpedia.org/resource/Combined_oral_contraceptive_pill +
, http://dbpedia.org/resource/Agonist +
, http://dbpedia.org/resource/Category:Hormonal_contraception +
, http://dbpedia.org/resource/Chemical_synthesis +
, http://dbpedia.org/resource/Chile +
, http://dbpedia.org/resource/Bioequivalent +
, http://dbpedia.org/resource/United_States +
, http://dbpedia.org/resource/Erectile_function +
, http://dbpedia.org/resource/Progestin +
, http://dbpedia.org/resource/Mestranol/norethisterone +
, http://dbpedia.org/resource/Estrogen_%28medication%29 +
, http://dbpedia.org/resource/Category:Synthetic_estrogens +
, http://dbpedia.org/resource/Estrane +
, http://dbpedia.org/resource/Breakthrough_bleeding +
, http://dbpedia.org/resource/Menopausal_hormone_therapy +
, http://dbpedia.org/resource/Gonadotropin +
, http://dbpedia.org/resource/Steroid +
, http://dbpedia.org/resource/United_Kingdom +
, http://dbpedia.org/resource/Estrogenic +
, http://dbpedia.org/resource/Synthetic_compound +
, http://dbpedia.org/resource/Nausea +
, http://dbpedia.org/resource/Category:Estranes +
, http://dbpedia.org/resource/Libido +
, http://dbpedia.org/resource/Liver +
, http://dbpedia.org/resource/Oral_administration +
, http://dbpedia.org/resource/G.D._Searle%2C_LLC +
, http://dbpedia.org/resource/File:Ethinylestradiol.svg +
, http://dbpedia.org/resource/Estradiol_%28medication%29 +
, http://dbpedia.org/resource/Birth_control_pill +
, http://dbpedia.org/resource/Biological_target +
, http://dbpedia.org/resource/Methyl_group +
, http://dbpedia.org/resource/Norethisterone +
, http://dbpedia.org/resource/Japan +
, http://dbpedia.org/resource/Ether +
, http://dbpedia.org/resource/Edema +
, http://dbpedia.org/resource/Ethinylestradiol +
, http://dbpedia.org/resource/Progestogen +
, http://dbpedia.org/resource/Category:Estrogen_ethers +
, http://dbpedia.org/resource/Mestranol/noretynodrel +
, http://dbpedia.org/resource/Sperm_count +
, http://dbpedia.org/resource/Ovulation +
, http://dbpedia.org/resource/Estrogen_ether +
, http://dbpedia.org/resource/Relative_binding_affinity +
, http://dbpedia.org/resource/Wastewater_treatment +
, http://dbpedia.org/resource/Chemical_derivative +
, http://dbpedia.org/resource/Elimination_half-life +
, http://dbpedia.org/resource/Breast_tension +
, http://dbpedia.org/resource/Male_contraceptive +
, http://dbpedia.org/resource/Pharmacokinetic +
|
| http://dbpedia.org/property/atcPrefix
|
None
|
| http://dbpedia.org/property/c
|
21
|
| http://dbpedia.org/property/casNumber
|
72
|
| http://dbpedia.org/property/chebi
|
6784
|
| http://dbpedia.org/property/chembl
|
1201151
|
| http://dbpedia.org/property/chemspiderid
|
6054
|
| http://dbpedia.org/property/class
|
http://dbpedia.org/resource/Estrogen_ether +
, http://dbpedia.org/resource/Estrogen_%28medication%29 +
|
| http://dbpedia.org/property/drugbank
|
DB01357
|
| http://dbpedia.org/property/eliminationHalfLife
|
-129600.0
, 3000.0
|
| http://dbpedia.org/property/h
|
26
|
| http://dbpedia.org/property/image
|
Mestranol molecule ball.png
|
| http://dbpedia.org/property/iupacName
|
-17
|
| http://dbpedia.org/property/iupharLigand
|
7087
|
| http://dbpedia.org/property/kegg
|
D00575
|
| http://dbpedia.org/property/legalStatus
|
Rx-only
|
| http://dbpedia.org/property/medlineplus
|
a601050
|
| http://dbpedia.org/property/metabolites
|
http://dbpedia.org/resource/Ethinylestradiol +
|
| http://dbpedia.org/property/o
|
2
|
| http://dbpedia.org/property/pubchem
|
6291
|
| http://dbpedia.org/property/routesOfAdministration
|
http://dbpedia.org/resource/Oral_administration +
|
| http://dbpedia.org/property/smiles
|
OC
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
IMSSROKUHAOUJS-MJCUULBUSA-N
|
| http://dbpedia.org/property/synonyms
|
Ethinylestradiol 3-methyl ether; EEME; EE3ME; CB-8027; L-33355; RS-1044; 17α-Ethynylestradiol 3-methyl ether; 17α-Ethynyl-3-methoxyestra-1,3,5-trien-17β-ol; 3-Methoxy-19-norpregna-1,3,5-trien-20-yn-17β-ol
|
| http://dbpedia.org/property/tradename
|
Enovid, Norinyl, Ortho-Novum, others
|
| http://dbpedia.org/property/unii
|
B2V233XGE7
|
| http://dbpedia.org/property/verifiedfields
|
verified
|
| http://dbpedia.org/property/verifiedrevid
|
462249106
|
| http://dbpedia.org/property/watchedfields
|
verified
|
| http://dbpedia.org/property/width
|
225
, 250
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Cascite +
, http://dbpedia.org/resource/Template:Chemspidercite +
, http://dbpedia.org/resource/Template:Estrogens_and_antiestrogens +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Abbr +
, http://dbpedia.org/resource/Template:Ebicite +
, http://dbpedia.org/resource/Template:Drugs.com +
, http://dbpedia.org/resource/Template:Drugbankcite +
, http://dbpedia.org/resource/Template:Estrogen_receptor_modulators +
, http://dbpedia.org/resource/Template:Short_description +
, http://dbpedia.org/resource/Template:Keggcite +
, http://dbpedia.org/resource/Template:Oral_potencies_of_estrogens +
, http://dbpedia.org/resource/Template:See_also +
, http://dbpedia.org/resource/Template:Affinities_and_estrogenic_potencies_of_estrogen_esters_and_ethers_at_the_estrogen_receptors +
, http://dbpedia.org/resource/Template:Fdacite +
, http://dbpedia.org/resource/Template:Drugbox +
, http://dbpedia.org/resource/Template:Stdinchicite +
, http://dbpedia.org/resource/Template:Abbrlink +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Estranes +
, http://dbpedia.org/resource/Category:Ethynyl_compounds +
, http://dbpedia.org/resource/Category:Synthetic_estrogens +
, http://dbpedia.org/resource/Category:Estrogen_ethers +
, http://dbpedia.org/resource/Category:Hormonal_contraception +
, http://dbpedia.org/resource/Category:Prodrugs +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Synthetic +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Mestranol?oldid=1123032923&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/Mestranol.svg +
, http://commons.wikimedia.org/wiki/Special:FilePath/Mestranol_molecule_ball.png +
, http://commons.wikimedia.org/wiki/Special:FilePath/Ethinylestradiol.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Mestranol +
|
| owl:sameAs |
http://pt.dbpedia.org/resource/Mestranol +
, http://dbpedia.org/resource/Mestranol +
, http://vi.dbpedia.org/resource/Mestranol +
, https://global.dbpedia.org/id/549Ya +
, http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB01357 +
, http://sr.dbpedia.org/resource/Mestranol +
, http://sh.dbpedia.org/resource/Mestranol +
, http://fa.dbpedia.org/resource/%D9%85%D8%B3%D8%AA%D8%B1%D8%A7%D9%86%D9%88%D9%84 +
, http://www.wikidata.org/entity/Q904308 +
, http://zh.dbpedia.org/resource/%E7%BE%8E%E9%9B%8C%E9%86%87 +
, http://rdf.freebase.com/ns/m.01xm8r_ +
, http://de.dbpedia.org/resource/Mestranol +
|
| rdf:type |
http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
, http://www.wikidata.org/entity/Q8386 +
, http://dbpedia.org/ontology/ChemicalSubstance +
, http://umbel.org/umbel/rc/DrugProduct +
, http://dbpedia.org/ontology/Drug +
|
| rdfs:comment |
Mestranol, sold under the brand names Enov … Mestranol, sold under the brand names Enovid, Norinyl, and Ortho-Novum among others, is an estrogen medication which has been used in birth control pills, menopausal hormone therapy, and the treatment of menstrual disorders. It is formulated in combination with a progestin and is not available alone. It is taken by mouth. Side effects of mestranol include nausea, breast tension, edema, and breakthrough bleeding among others. It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. Mestranol is a prodrug of ethinylestradiol in the body.a prodrug of ethinylestradiol in the body.
, O mestranol (DCI; nomes de marca: Devocin, … O mestranol (DCI; nomes de marca: Devocin, Ovastol, Tranel, entre outros; também conhecido como etinilestradiol 3-metil éter, EEME, EE3ME) é um estrogênio esteroide sintético amplamente utilizado para fins contraceptivos. Foi empregado como o componente do estrogênico em muitos dos primeiros contraceptivos orais, tais como o mestranol / noretynodrel (nomes de tipo Enovid, Enavid), e é usado ainda hoje. Foi também um componente de Ortho-Novum, Ortho-Novin, Femigen, e Norbiogest. Além do seu uso como contraceptivo oral, o mestranol tem sido usado como um componente da terapia de reposição hormonal.mponente da terapia de reposição hormonal.
, Mestranol ist ein synthetischer Arzneistoff aus der Gruppe der Estrogene. Es ist ein Prodrug (eine inaktive Vorstufe) des häufig in Arzneimitteln zur Empfängnisverhütung eingesetzten Ethinylestradiols.
|
| rdfs:label |
美雌醇
, Mestranol
|
| rdfs:seeAlso |
http://dbpedia.org/resource/Ethinylestradiol +
, http://dbpedia.org/resource/List_of_estrogens +
|
