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http://dbpedia.org/ontology/abstract 中介運輸(Mediated transport)是指由載體蛋白介導的運輸。人體中的物中介運輸(Mediated transport)是指由載體蛋白介導的運輸。人體中的物質可以是疏水的、親電的,含有正電荷或負電荷的物質,或具有其他性質。因此,有時這些物質可能無法通過不依賴蛋白質的運動穿過細胞膜。細胞膜內嵌有許多載體蛋白,這些蛋白可以使這些分子進入和流出細胞。有三種類型的載體蛋白:單向運輸載體、和。可以運輸的物質包括營養素、離子、葡萄糖等,所有這些都取決於細胞的需求。分子將與載體蛋白結合,從而改變其形狀。形狀的改變或其他添加的物質(例如ATP)將依次導致載體蛋白改變其形狀,並將分子釋放到細胞膜的另一側。添加的物質(例如ATP)將依次導致載體蛋白改變其形狀,並將分子釋放到細胞膜的另一側。 , El transporte mediado se refiere al transpEl transporte mediado se refiere al transporte mediado por una proteína de transporte de membrana. Las sustancias en el cuerpo humano pueden ser hidrofóbicas, electrofílicas, contener una carga positiva o negativa, o tener otra propiedad. Como tal, hay momentos en que esas sustancias no pueden atravesar la membrana celular utilizando un movimiento independiente de proteínas.​ La membrana celular está incrustada con muchas proteínas de transporte de membrana que permiten que dichas moléculas entren y salgan de la célula.​ Una molécula se unirá a una proteína transportadora, alterando su forma. El cambio de forma u otras sustancias añadidas como ATP, a su vez, harán que la proteína de transporte altere su forma y libere la molécula al otro lado de la membrana celular.​cula al otro lado de la membrana celular.​ , Mediated transport refers to transport medMediated transport refers to transport mediated by a membrane transport protein. Substances in the human body may be hydrophobic, electrophilic, contain a positively or negatively charge, or have another property. As such there are times when those substances may not be able to pass over the cell membrane using protein-independent movement. The cell membrane is imbedded with many membrane transport proteins that allow such molecules to travel in and out of the cell. There are three types of mediated transporters: uniport, symport, and antiport. Things that can be transported are nutrients, ions, glucose, etc, all depending on the needs of the cell. One example of a uniport mediated transport protein is GLUT1. GLUT1 is a transmembrane protein, which means it spans the entire width of the cell membrane, connecting the extracellular and intracellular region. It is a uniport system because it specifically transports glucose in only one direction, down its concentration gradient across the cell membrane. Another example of a uniporter mediated transport protein is microsomal triglyceride transfer protein (MTTP) who is responsible for catalyzing the assembly of the triglyceride rich lipoproteins as well mediating their release from the lumen of the endoplasmic reticulum. What is distinguishable about this specific transfer protein is that it requires the protein PRAP1 to bind to the lipoprotein to facilitate the transport of said lipoprotein. MTTP only recognizes the PRAP1-lipoprotein complex and only then will it catalyze the transport reaction. In a way, the PRAP1 protein acts as a signal for MTTP. The importance of such interactions implies that mediated transport is not only dependent on transmembrane proteins but can also require the presence of additional non-transmembrane proteins. For instance, studies show that in the absence of a fully functional PRAP1 protein, MTTP fails to transport specific lipoproteins across the endoplasmic reticulum membrane. An example of a symporter mediated transport protein is SGLT1, a sodium/glucose co-transporter protein that is mainly found in the intestinal tract. The SGLT1 protein is a symporter system because it passes both glucose and sodium in the same direction, from the lumen of the intestine to inside the intestinal cells. An example of an antiporter mediated transport protein is the sodium-calcium antiporter, a transport protein involved in keeping the cytoplasmic concentration of calcium ions in the cells, low. This transport protein is an antiporter system because it transports three sodium ions across the plasma membrane in exchange for a calcium ion, which is transported in the opposite direction. Mechanism of transport. A molecule will bind to a transporter protein, altering its shape. The change of shape or other added substances such as ATP will, in turn, cause the transport protein to alter its shape and release the molecule onto the other side of the cell membrane. onto the other side of the cell membrane. , Transporte mediado é um tipo de transporteTransporte mediado é um tipo de transporte realizado através da membrana celular. Este transporte é caracterizado por necessitar de proteínas transportadoras (permeases) para a sua realização, necessitando também dos processos físicos que ocorrem dentro (meio intracelular) e fora (meio extracelular) da célula . Existem dois tipos deste transporte: * Difusão facilitada * Transporte activo * Osmose facilitada * Transporte activo * Osmose
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rdfs:comment 中介運輸(Mediated transport)是指由載體蛋白介導的運輸。人體中的物中介運輸(Mediated transport)是指由載體蛋白介導的運輸。人體中的物質可以是疏水的、親電的,含有正電荷或負電荷的物質,或具有其他性質。因此,有時這些物質可能無法通過不依賴蛋白質的運動穿過細胞膜。細胞膜內嵌有許多載體蛋白,這些蛋白可以使這些分子進入和流出細胞。有三種類型的載體蛋白:單向運輸載體、和。可以運輸的物質包括營養素、離子、葡萄糖等,所有這些都取決於細胞的需求。分子將與載體蛋白結合,從而改變其形狀。形狀的改變或其他添加的物質(例如ATP)將依次導致載體蛋白改變其形狀,並將分子釋放到細胞膜的另一側。添加的物質(例如ATP)將依次導致載體蛋白改變其形狀,並將分子釋放到細胞膜的另一側。 , Mediated transport refers to transport medMediated transport refers to transport mediated by a membrane transport protein. Substances in the human body may be hydrophobic, electrophilic, contain a positively or negatively charge, or have another property. As such there are times when those substances may not be able to pass over the cell membrane using protein-independent movement. The cell membrane is imbedded with many membrane transport proteins that allow such molecules to travel in and out of the cell. There are three types of mediated transporters: uniport, symport, and antiport. Things that can be transported are nutrients, ions, glucose, etc, all depending on the needs of the cell. One example of a uniport mediated transport protein is GLUT1. GLUT1 is a transmembrane protein, which means it spans the entire width of the ce means it spans the entire width of the ce , Transporte mediado é um tipo de transporteTransporte mediado é um tipo de transporte realizado através da membrana celular. Este transporte é caracterizado por necessitar de proteínas transportadoras (permeases) para a sua realização, necessitando também dos processos físicos que ocorrem dentro (meio intracelular) e fora (meio extracelular) da célula . Existem dois tipos deste transporte: * Difusão facilitada * Transporte activo * Osmose facilitada * Transporte activo * Osmose , El transporte mediado se refiere al transpEl transporte mediado se refiere al transporte mediado por una proteína de transporte de membrana. Las sustancias en el cuerpo humano pueden ser hidrofóbicas, electrofílicas, contener una carga positiva o negativa, o tener otra propiedad. Como tal, hay momentos en que esas sustancias no pueden atravesar la membrana celular utilizando un movimiento independiente de proteínas.​ La membrana celular está incrustada con muchas proteínas de transporte de membrana que permiten que dichas moléculas entren y salgan de la célula.​ Una molécula se unirá a una proteína transportadora, alterando su forma. El cambio de forma u otras sustancias añadidas como ATP, a su vez, harán que la proteína de transporte altere su forma y libere la molécula al otro lado de la membrana celular.​cula al otro lado de la membrana celular.​
rdfs:label Transporte mediado , 媒介傳遞 , Mediated transport
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