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ML-154 (NCGC-84) is a drug which acts as a … ML-154 (NCGC-84) is a drug which acts as a selective, non-peptide antagonist at the neuropeptide S receptor NPSR. In animal studies it decreases self-administration of alcohol in addicted rats, and lowers motivation for alcohol rewards, suggesting a potential application for NPS antagonists in the treatment of alcoholism.ntagonists in the treatment of alcoholism.
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