http://dbpedia.org/ontology/abstract
|
JWH-146 (1-heptyl-5-phenyl-1H-pyrrol-3-yl) … JWH-146 (1-heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenyl-methanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB1 (Ki = 21 ± 2nM) and CB2 (Ki = 62 ± 5nM) receptors, with a moderate (~2.9x) selectivity for the CB1 receptor over the CB2 receptor. JWH-146 was first synthesized in 2006 by John W. Huffman and colleagues to examine the nature of ligand binding to the CB1 receptor.ure of ligand binding to the CB1 receptor.
|
http://dbpedia.org/ontology/casNumber
|
914458-21-2
|
http://dbpedia.org/ontology/chEMBL
|
219970
|
http://dbpedia.org/ontology/fdaUniiCode
|
5446SVK6LH
|
http://dbpedia.org/ontology/pubchem
|
44418308
|
http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/JWH-146.svg?width=300 +
|
http://dbpedia.org/ontology/wikiPageID
|
68619382
|
http://dbpedia.org/ontology/wikiPageLength
|
4021
|
http://dbpedia.org/ontology/wikiPageRevisionID
|
1102142553
|
http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Synthetic_cannabinoid +
, http://dbpedia.org/resource/Category:CB1_receptor_agonists +
, http://dbpedia.org/resource/Category:CB2_receptor_agonists +
, http://dbpedia.org/resource/Cannabinoid_receptor_2 +
, http://dbpedia.org/resource/Category:Naphthoylpyrroles +
, http://dbpedia.org/resource/Category:Designer_drugs +
, http://dbpedia.org/resource/Misuse_of_Drugs_Act_1971 +
, http://dbpedia.org/resource/Cannabinoid_receptor_1 +
, http://dbpedia.org/resource/John_W._Huffman +
, http://dbpedia.org/resource/Controlled_Drugs_and_Substances_Act +
, http://dbpedia.org/resource/List_of_JWH_cannabinoids +
, http://dbpedia.org/resource/Category:JWH_cannabinoids +
|
http://dbpedia.org/property/c
|
28
|
http://dbpedia.org/property/casNumber
|
914458
|
http://dbpedia.org/property/chembl
|
219970
|
http://dbpedia.org/property/chemspiderid
|
23277883
|
http://dbpedia.org/property/h
|
29
|
http://dbpedia.org/property/iupacName
|
-1
|
http://dbpedia.org/property/legalCa
|
Schedule II
|
http://dbpedia.org/property/legalUk
|
Class B
|
http://dbpedia.org/property/n
|
1
|
http://dbpedia.org/property/o
|
1
|
http://dbpedia.org/property/pubchem
|
44418308
|
http://dbpedia.org/property/smiles
|
O=CC3=CNC=C3
|
http://dbpedia.org/property/stdinchi
|
1
|
http://dbpedia.org/property/stdinchikey
|
JDBFNFBWXVCTSA-UHFFFAOYSA-N
|
http://dbpedia.org/property/unii
|
5446
|
http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Cannabinoid-stub +
, http://dbpedia.org/resource/Template:Cannabinoids +
, http://dbpedia.org/resource/Template:Stdinchicite +
, http://dbpedia.org/resource/Template:Drugbankcite +
, http://dbpedia.org/resource/Template:Ebicite +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Short_description +
, http://dbpedia.org/resource/Template:Cascite +
, http://dbpedia.org/resource/Template:Drugbox +
, http://dbpedia.org/resource/Template:Chemspidercite +
, http://dbpedia.org/resource/Template:Cn +
, http://dbpedia.org/resource/Template:Fdacite +
|
http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:JWH_cannabinoids +
, http://dbpedia.org/resource/Category:CB1_receptor_agonists +
, http://dbpedia.org/resource/Category:CB2_receptor_agonists +
, http://dbpedia.org/resource/Category:Designer_drugs +
, http://dbpedia.org/resource/Category:Naphthoylpyrroles +
|
http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/JWH-146?oldid=1102142553&ns=0 +
|
http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/JWH-146.svg +
|
http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/JWH-146 +
|
owl:sameAs |
http://dbpedia.org/resource/JWH-146 +
, http://www.wikidata.org/entity/Q108401005 +
, https://global.dbpedia.org/id/G5AEU +
|
rdf:type |
http://dbpedia.org/ontology/ChemicalSubstance +
, http://www.wikidata.org/entity/Q8386 +
, http://dbpedia.org/ontology/Drug +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
|
rdfs:comment |
JWH-146 (1-heptyl-5-phenyl-1H-pyrrol-3-yl) … JWH-146 (1-heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenyl-methanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB1 (Ki = 21 ± 2nM) and CB2 (Ki = 62 ± 5nM) receptors, with a moderate (~2.9x) selectivity for the CB1 receptor over the CB2 receptor. JWH-146 was first synthesized in 2006 by John W. Huffman and colleagues to examine the nature of ligand binding to the CB1 receptor.ure of ligand binding to the CB1 receptor.
|
rdfs:label |
JWH-146
|