| http://dbpedia.org/ontology/abstract
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In molecular biology, glycoside hydrolase … In molecular biology, glycoside hydrolase family 33 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. This family contains sialidases (CAZY GH_33), which hydrolyse alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. Sialidases may act as pathogenic factors in microbial infections. The 1.8 A structure of trans-sialidase from leech (Macrobdella decora, Q27701) in complex with 2-deoxy-2, 3-didehydro-NeuAc was solved. The refined model comprising residues 81-769 has a catalytic beta-propeller domain, a N-terminal lectin-like domain and an irregular beta-stranded domain inserted into the catalytic domain.domain inserted into the catalytic domain.
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| http://dbpedia.org/ontology/symbol
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Sialidase
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33302030
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4800
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| http://dbpedia.org/property/cazy
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GH33
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| http://dbpedia.org/property/interpro
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IPR004124
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| http://dbpedia.org/property/name
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Sialidase, N-terminal domain
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| http://dbpedia.org/property/pfam
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PF02973
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| http://dbpedia.org/property/scop
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1
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| http://dbpedia.org/property/symbol
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Sialidase
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| rdfs:comment |
In molecular biology, glycoside hydrolase … In molecular biology, glycoside hydrolase family 33 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.cyclopedia of carbohydrate active enzymes.
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| rdfs:label |
Glycoside hydrolase family 33
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