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Echinomycin is a peptide antibiotic. It is … Echinomycin is a peptide antibiotic. It is a dimer of two peptides creating a cyclic structure. It contains a bicyclic aromatic chromophore that is attached to the dimerized cyclic peptide core and a thioacetal bridge. It intercalates into DNA at two specific sites, thereby blocking the binding of hypoxia inducible factor 1 alpha (HIF1alpha).oxia inducible factor 1 alpha (HIF1alpha).
, L'échinomycine ou lévomycine ou quinomycin … L'échinomycine ou lévomycine ou quinomycine A est un antibiotique polypeptidique cytotoxique contenant deux substituants quinoxaline qui se lie à l'ADN et inhibe la synthèse des ARN. Il s'intercale dans l'ADN sur deux sites spécifiques, bloquant ainsi la fixation du facteur HIF1alpha (hypoxia inducible factor 1 alpha).1alpha (hypoxia inducible factor 1 alpha).
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Quinomycin A; Levomycin
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Quinomycin A; Levomycin
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| rdfs:comment |
Echinomycin is a peptide antibiotic. It is … Echinomycin is a peptide antibiotic. It is a dimer of two peptides creating a cyclic structure. It contains a bicyclic aromatic chromophore that is attached to the dimerized cyclic peptide core and a thioacetal bridge. It intercalates into DNA at two specific sites, thereby blocking the binding of hypoxia inducible factor 1 alpha (HIF1alpha).oxia inducible factor 1 alpha (HIF1alpha).
, L'échinomycine ou lévomycine ou quinomycin … L'échinomycine ou lévomycine ou quinomycine A est un antibiotique polypeptidique cytotoxique contenant deux substituants quinoxaline qui se lie à l'ADN et inhibe la synthèse des ARN. Il s'intercale dans l'ADN sur deux sites spécifiques, bloquant ainsi la fixation du facteur HIF1alpha (hypoxia inducible factor 1 alpha).1alpha (hypoxia inducible factor 1 alpha).
|
| rdfs:label |
Echinomycin
, Échinomycine
|
