| http://dbpedia.org/ontology/abstract
|
Distigmin (auch: Hexamarium Bromid, Distig … Distigmin (auch: Hexamarium Bromid, Distigmin-Bromid) ist der Freiname für ein indirektes Parasympathomimetikum mit langer Wirkdauer. Es weist ein ähnliches Wirkungsprofil wie Neostigmin und Pyridostigmin auf und findet bei neurogener Blasenentleerungsstörung mit Erschlaffung des Blasenmuskels, hypotoner chronischer Verstopfung, der Hirschsprung-Krankheit, peripheren Lähmungen der quergestreiften Muskulatur oder Myasthenia gravis Verwendung als Arzneimittel. Der verwendete Wirkstoff ist Distigmin-Bromid; er wurde 1957 von den Österreichischen Stickstoffwerken patentiert und kam 1959 in den Handel.ken patentiert und kam 1959 in den Handel.
, Distygmina – organiczny związek chemiczny, lek pobudzający działanie układu nerwowego przywspółczulnego i mięśniowego. Działa na mięśnie gładkie przewodu pokarmowego, rozszerza naczynia krwionośne, poprawia przepływ krwi, zwalnia akcję serca.
, Дистигмина бромид (Distigmine bromide)*. 3-Окси-1-метилпиридиний гексаметилен-бис-N-метилккарбамата дибромид. Синонимы: Убретид, Hexfmarium bromide, Ubretid, Ubretil. Является ингибитором холинэстеразы длительного действия.
, La distigmina, in genere commercializzata … La distigmina, in genere commercializzata come sale bromuro di distigmina, è un inibitore della colinesterasi, reversibile, con azione farmacologica molto simile a quella della piridostigmina e della neostigmina, ma più prolungata nel tempo. Chimicamente la molecola è un composto quaternario di ammonio.Il composto non è in vendita in Italia, ma in alcuni paesi europei (ad esempio nel Regno Unito) è venduto dalla società farmaceutica Sanofi-Aventis con il nome commerciale di Ubretid nella forma farmaceutica di compresse contenenti 5 mg di principio attivo.resse contenenti 5 mg di principio attivo.
, Distigmine (as distigmine bromide) is a pa … Distigmine (as distigmine bromide) is a parasympathomimetic. Distigmine is similar to pyridostigmine and neostigmine but has a longer duration of action. It is available as tablets on prescription only. It is commonly used to treat various conditions, including myasthenia gravis and underactive bladder. Distigmine has a greater risk of causing cholinergic crisis because of accumulation of the drug being more likely than with neostigmine or pyridostigmine and so distigmine is rarely used as a treatment for myasthenia gravis, unlike pyridostigmine and neostigmine.is, unlike pyridostigmine and neostigmine.
, ジスチグミン（distigmine）とは、コリンエステラーゼ阻害薬の1つである。
|
| http://dbpedia.org/ontology/bioavailability
|
4.6500000953674
|
| http://dbpedia.org/ontology/casNumber
|
17299-00-2
, 15876-67-2
|
| http://dbpedia.org/ontology/chEBI
|
31512
|
| http://dbpedia.org/ontology/chEMBL
|
1098285
|
| http://dbpedia.org/ontology/fdaUniiCode
|
T940307O7B
, 750F36OP6J
|
| http://dbpedia.org/ontology/kegg
|
D01228
|
| http://dbpedia.org/ontology/pubchem
|
27522
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/Distigmine_bromide.svg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageID
|
12499049
|
| http://dbpedia.org/ontology/wikiPageLength
|
3721
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1095955422
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Category:Biscarbamates +
, http://dbpedia.org/resource/Category:Bisquaternary_anticholinesterases +
, http://dbpedia.org/resource/Neostigmine +
, http://dbpedia.org/resource/Category:Aromatic_carbamates +
, http://dbpedia.org/resource/Cholinergic_crisis +
, http://dbpedia.org/resource/Category:Acetylcholinesterase_inhibitors +
, http://dbpedia.org/resource/Category:Pyridinium_compounds +
, http://dbpedia.org/resource/Parasympathomimetic +
, http://dbpedia.org/resource/Pyridostigmine +
, http://dbpedia.org/resource/Oral_administration +
|
| http://dbpedia.org/property/atcPrefix
|
N07
|
| http://dbpedia.org/property/atcSuffix
|
AA03
|
| http://dbpedia.org/property/bioavailability
|
4.65
|
| http://dbpedia.org/property/br
|
2
|
| http://dbpedia.org/property/c
|
22
|
| http://dbpedia.org/property/caption
|
Distigmine bromide
|
| http://dbpedia.org/property/casNumber
|
17299
, 15876
|
| http://dbpedia.org/property/chebi
|
31512
|
| http://dbpedia.org/property/chembl
|
1098285
|
| http://dbpedia.org/property/chemspiderid
|
25613
|
| http://dbpedia.org/property/eliminationHalfLife
|
234000.0
|
| http://dbpedia.org/property/excretion
|
renal
|
| http://dbpedia.org/property/h
|
32
|
| http://dbpedia.org/property/index2Label
|
bromide
|
| http://dbpedia.org/property/iupacName
|
hexyl}carbamate dibromide
, oxycarbonylamino]
, N-methyl-N-{6-[methyl-
|
| http://dbpedia.org/property/kegg
|
D01228
|
| http://dbpedia.org/property/n
|
4
|
| http://dbpedia.org/property/o
|
4
|
| http://dbpedia.org/property/pubchem
|
27522
|
| http://dbpedia.org/property/routesOfAdministration
|
By mouth, i.m.
|
| http://dbpedia.org/property/smiles
|
[Br-].[Br-].O=CNC
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
GJHSNEVFXQVOHR-UHFFFAOYSA-L
|
| http://dbpedia.org/property/unii
|
750
, T940307O7B
|
| http://dbpedia.org/property/verifiedfields
|
changed
|
| http://dbpedia.org/property/verifiedrevid
|
443699749
|
| http://dbpedia.org/property/width
|
250
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Stdinchicite +
, http://dbpedia.org/resource/Template:Keggcite +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Cascite +
, http://dbpedia.org/resource/Template:Chemspidercite +
, http://dbpedia.org/resource/Template:Nervous-system-drug-stub +
, http://dbpedia.org/resource/Template:Drugbox +
, http://dbpedia.org/resource/Template:Ebicite +
, http://dbpedia.org/resource/Template:Fdacite +
, http://dbpedia.org/resource/Template:Drugbankcite +
, http://dbpedia.org/resource/Template:Acetylcholine_metabolism_and_transport_modulators +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Bisquaternary_anticholinesterases +
, http://dbpedia.org/resource/Category:Biscarbamates +
, http://dbpedia.org/resource/Category:Aromatic_carbamates +
, http://dbpedia.org/resource/Category:Acetylcholinesterase_inhibitors +
, http://dbpedia.org/resource/Category:Pyridinium_compounds +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Distigmine?oldid=1095955422&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/Distigmine_bromide.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Distigmine +
|
| owl:sameAs |
http://ja.dbpedia.org/resource/%E3%82%B8%E3%82%B9%E3%83%81%E3%82%B0%E3%83%9F%E3%83%B3 +
, http://sr.dbpedia.org/resource/Distigmin +
, http://ru.dbpedia.org/resource/%D0%94%D0%B8%D1%81%D1%82%D0%B8%D0%B3%D0%BC%D0%B8%D0%BD%D0%B0_%D0%B1%D1%80%D0%BE%D0%BC%D0%B8%D0%B4 +
, http://fi.dbpedia.org/resource/Distigmiini +
, http://www.wikidata.org/entity/Q3277473 +
, http://rdf.freebase.com/ns/m.02w93tt +
, https://global.dbpedia.org/id/32Miz +
, http://pl.dbpedia.org/resource/Distygmina +
, http://sh.dbpedia.org/resource/Distigmin +
, http://de.dbpedia.org/resource/Distigmin +
, http://dbpedia.org/resource/Distigmine +
, http://it.dbpedia.org/resource/Distigmina +
, http://yago-knowledge.org/resource/Distigmine +
|
| rdf:type |
http://dbpedia.org/class/yago/PhysicalEntity100001930 +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
, http://dbpedia.org/class/yago/WikicatCarbamates +
, http://dbpedia.org/class/yago/WikicatQuaternaryAmmoniumCompounds +
, http://umbel.org/umbel/rc/DrugProduct +
, http://dbpedia.org/class/yago/Carbamate114792281 +
, http://dbpedia.org/class/yago/Relation100031921 +
, http://dbpedia.org/class/yago/QuaternaryAmmoniumCompound114691231 +
, http://dbpedia.org/class/yago/Part113809207 +
, http://dbpedia.org/ontology/ChemicalSubstance +
, http://dbpedia.org/class/yago/Compound114818238 +
, http://dbpedia.org/class/yago/Chemical114806838 +
, http://dbpedia.org/class/yago/Substance100019613 +
, http://dbpedia.org/class/yago/Matter100020827 +
, http://dbpedia.org/class/yago/OrganicCompound114727670 +
, http://dbpedia.org/class/yago/Material114580897 +
, http://dbpedia.org/class/yago/Abstraction100002137 +
, http://dbpedia.org/ontology/Drug +
, http://www.wikidata.org/entity/Q8386 +
, http://dbpedia.org/class/yago/Salt115010703 +
|
| rdfs:comment |
Distygmina – organiczny związek chemiczny, lek pobudzający działanie układu nerwowego przywspółczulnego i mięśniowego. Działa na mięśnie gładkie przewodu pokarmowego, rozszerza naczynia krwionośne, poprawia przepływ krwi, zwalnia akcję serca.
, Дистигмина бромид (Distigmine bromide)*. 3-Окси-1-метилпиридиний гексаметилен-бис-N-метилккарбамата дибромид. Синонимы: Убретид, Hexfmarium bromide, Ubretid, Ubretil. Является ингибитором холинэстеразы длительного действия.
, ジスチグミン（distigmine）とは、コリンエステラーゼ阻害薬の1つである。
, La distigmina, in genere commercializzata … La distigmina, in genere commercializzata come sale bromuro di distigmina, è un inibitore della colinesterasi, reversibile, con azione farmacologica molto simile a quella della piridostigmina e della neostigmina, ma più prolungata nel tempo. Chimicamente la molecola è un composto quaternario di ammonio.Il composto non è in vendita in Italia, ma in alcuni paesi europei (ad esempio nel Regno Unito) è venduto dalla società farmaceutica Sanofi-Aventis con il nome commerciale di Ubretid nella forma farmaceutica di compresse contenenti 5 mg di principio attivo.resse contenenti 5 mg di principio attivo.
, Distigmine (as distigmine bromide) is a pa … Distigmine (as distigmine bromide) is a parasympathomimetic. Distigmine is similar to pyridostigmine and neostigmine but has a longer duration of action. It is available as tablets on prescription only. It is commonly used to treat various conditions, including myasthenia gravis and underactive bladder. Distigmine has a greater risk of causing cholinergic crisis because of accumulation of the drug being more likely than with neostigmine or pyridostigmine and so distigmine is rarely used as a treatment for myasthenia gravis, unlike pyridostigmine and neostigmine.is, unlike pyridostigmine and neostigmine.
, Distigmin (auch: Hexamarium Bromid, Distig … Distigmin (auch: Hexamarium Bromid, Distigmin-Bromid) ist der Freiname für ein indirektes Parasympathomimetikum mit langer Wirkdauer. Es weist ein ähnliches Wirkungsprofil wie Neostigmin und Pyridostigmin auf und findet bei neurogener Blasenentleerungsstörung mit Erschlaffung des Blasenmuskels, hypotoner chronischer Verstopfung, der Hirschsprung-Krankheit, peripheren Lähmungen der quergestreiften Muskulatur oder Myasthenia gravis Verwendung als Arzneimittel.thenia gravis Verwendung als Arzneimittel.
|
| rdfs:label |
Distygmina
, Distigmin
, Distigmina
, Distigmine
, Дистигмина бромид
, ジスチグミン
|
