| http://dbpedia.org/ontology/abstract
|
The dermal equivalent, also known as derma … The dermal equivalent, also known as dermal replacement or neodermis, is an in vitro model of the dermal layer of skin. There is no specific way of forming a dermal equivalent, however the first dermal equivalent was constructed by seeding dermal fibroblasts into a collagen gel. This gel may then be allowed to contract as a model of wound contraction. This collagen gel contraction assay may be used to screen for treatments which promote or inhibit contraction and thus affect the development of a scar. Other cell types may be incorporated into the dermal equivalent to increase the complexity of the model. For example, keratinocytes may be seeded on the surface to create a skin equivalent, or macrophages may be incorporated to model the inflammatory phase of wound healing. A number of commercial dermal equivalents with different compositions and development methods are available. These include Integra, AlloDerm, and Dermagraft, among others.a, AlloDerm, and Dermagraft, among others.
|
| http://dbpedia.org/ontology/wikiPageExternalLink
|
https://dermagraft.com +
, https://hcp.alloderm.com +
, https://www.integralife.com/home +
|
| http://dbpedia.org/ontology/wikiPageID
|
25432204
|
| http://dbpedia.org/ontology/wikiPageLength
|
13290
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1070324629
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Ross_Granville_Harrison +
, http://dbpedia.org/resource/Collagen +
, http://dbpedia.org/resource/Collagen_gel_contraction_assay +
, http://dbpedia.org/resource/Extracellular_matrix_proteins +
, http://dbpedia.org/resource/Dermal_fibroblast +
, http://dbpedia.org/resource/Eschar +
, http://dbpedia.org/resource/Wound_healing +
, http://dbpedia.org/resource/Gingival_grafting +
, http://dbpedia.org/resource/Regeneration_in_humans +
, http://dbpedia.org/resource/Autotransplantation +
, http://dbpedia.org/resource/Regenerative_medicine +
, http://dbpedia.org/resource/Glutaraldehyde +
, http://dbpedia.org/resource/Keratinocytes +
, http://dbpedia.org/resource/Macrophages +
, http://dbpedia.org/resource/Wound_contraction +
, http://dbpedia.org/resource/Polysiloxane +
, http://dbpedia.org/resource/Chondroitin_sulfate +
, http://dbpedia.org/resource/In_vitro +
, http://dbpedia.org/resource/Oculoplastics +
, http://dbpedia.org/resource/Diabetic_foot_ulcer +
, http://dbpedia.org/resource/Scar +
, http://dbpedia.org/resource/Integra_LifeSciences +
, http://dbpedia.org/resource/Artificial_skin +
, http://dbpedia.org/resource/Acellular_dermis +
, http://dbpedia.org/resource/Fibroblast +
, http://dbpedia.org/resource/Tissue_engineering +
, http://dbpedia.org/resource/Silastic +
, http://dbpedia.org/resource/John_F._Burke +
, http://dbpedia.org/resource/Polyglactin +
, http://dbpedia.org/resource/Cadaver +
, http://dbpedia.org/resource/Skin_equivalent +
, http://dbpedia.org/resource/Category:Skin_physiology +
, http://dbpedia.org/resource/Dermis +
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Reflist +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Skin_physiology +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Dermal_equivalent?oldid=1070324629&ns=0 +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Dermal_equivalent +
|
| owl:sameAs |
http://rdf.freebase.com/ns/m.09k5lw7 +
, http://dbpedia.org/resource/Dermal_equivalent +
, https://global.dbpedia.org/id/4iSrB +
, http://www.wikidata.org/entity/Q5262667 +
|
| rdfs:comment |
The dermal equivalent, also known as derma … The dermal equivalent, also known as dermal replacement or neodermis, is an in vitro model of the dermal layer of skin. There is no specific way of forming a dermal equivalent, however the first dermal equivalent was constructed by seeding dermal fibroblasts into a collagen gel. This gel may then be allowed to contract as a model of wound contraction. This collagen gel contraction assay may be used to screen for treatments which promote or inhibit contraction and thus affect the development of a scar. Other cell types may be incorporated into the dermal equivalent to increase the complexity of the model. For example, keratinocytes may be seeded on the surface to create a skin equivalent, or macrophages may be incorporated to model the inflammatory phase of wound healing.l the inflammatory phase of wound healing.
|
| rdfs:label |
Dermal equivalent
|
