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Conjunctival squamous cell carcinoma (conj … Conjunctival squamous cell carcinoma (conjunctival SCC) and corneal intraepithelial neoplasia comprise what are called ocular surface squamous cell neoplasias. SCC is the most common malignancy of the conjunctiva in the US, with a yearly incidence of 1–2.8 per 100,000. Risk factors for the disease are exposure to sun (specifically occupational), exposure to UVB, and light-colored skin. Other risk factors include radiation, smoking, HPV, arsenic, and exposure to . Conjunctival SCC is often asymptomatic at first, but it can present with the presence of a growth, red eye, pain, itching, burning, tearing, sensitivity to light, double vision, and decreased vision.Spread of conjunctival SCC can occur in 1–21% of cases, with the first site of spread being the regional lymph nodes. Mortality for conjunctival SCC ranges from 0–8%.Diagnosis is often made by biopsy, as well as CT (in the case of invasive SCC). Treatment of conjunctival SCC is usually surgical excision followed by cryotherapy. After this procedure, Conjunctival SCC can recur 8–40% of the time. Radiation treatment, topical Mitomycin C, and removal of the contents of the orbit, or exenteration, are other methods of treatment. Close follow-up is recommended, because the average time to recurrence is 8–22 months.average time to recurrence is 8–22 months.
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Conjunctival squamous cell carcinoma (conj … Conjunctival squamous cell carcinoma (conjunctival SCC) and corneal intraepithelial neoplasia comprise what are called ocular surface squamous cell neoplasias. SCC is the most common malignancy of the conjunctiva in the US, with a yearly incidence of 1–2.8 per 100,000. Risk factors for the disease are exposure to sun (specifically occupational), exposure to UVB, and light-colored skin. Other risk factors include radiation, smoking, HPV, arsenic, and exposure to ., smoking, HPV, arsenic, and exposure to .
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