| http://dbpedia.org/ontology/abstract
|
Cerlapirdine (USAN; SAM-531, WAY-262,531, … Cerlapirdine (USAN; SAM-531, WAY-262,531, PF-05212365) is a drug which was under development by Wyeth/Pfizer for the treatment of cognitive disorders associated with Alzheimer's disease and schizophrenia. In a phase II clinical trial it demonstrated a trend toward efficacy along with a good side effect profile and no incidence of serious adverse events, but no further development has occurred since 2011. It exerts its effects by acting as a selective 5-HT6 receptor antagonist. as a selective 5-HT6 receptor antagonist.
|
| http://dbpedia.org/ontology/casNumber
|
925447-04-7 (hydrochloride)
, 925448-93-7
|
| http://dbpedia.org/ontology/chEMBL
|
2103880
|
| http://dbpedia.org/ontology/fdaUniiCode
|
EK40PJ0V49
|
| http://dbpedia.org/ontology/kegg
|
D10099
|
| http://dbpedia.org/ontology/pubchem
|
16071605
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/Cerlapirdine.svg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageID
|
33530675
|
| http://dbpedia.org/ontology/wikiPageLength
|
2677
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1120768438
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/Drug_development +
, http://dbpedia.org/resource/Hydrochloride +
, http://dbpedia.org/resource/Wyeth +
, http://dbpedia.org/resource/Clinical_trial +
, http://dbpedia.org/resource/Pfizer +
, http://dbpedia.org/resource/Drug +
, http://dbpedia.org/resource/Cognitive_disorder +
, http://dbpedia.org/resource/Schizophrenia +
, http://dbpedia.org/resource/Alzheimer%27s_disease +
, http://dbpedia.org/resource/Category:1-Naphthyl_compounds +
, http://dbpedia.org/resource/Latrepirdine +
, http://dbpedia.org/resource/Side_effect +
, http://dbpedia.org/resource/Receptor_antagonist +
, http://dbpedia.org/resource/5-HT6_receptor +
, http://dbpedia.org/resource/Category:Dimethylamino_compounds +
, http://dbpedia.org/resource/United_States_Adopted_Name +
, http://dbpedia.org/resource/Idalopirdine +
, http://dbpedia.org/resource/Category:Abandoned_drugs +
, http://dbpedia.org/resource/Phases_of_clinical_research +
, http://dbpedia.org/resource/Binding_selectivity +
|
| http://dbpedia.org/property/atcPrefix
|
none
|
| http://dbpedia.org/property/c
|
22
|
| http://dbpedia.org/property/casNumber
|
925448
|
| http://dbpedia.org/property/casSupplemental
|
925447
|
| http://dbpedia.org/property/chembl
|
2103880
|
| http://dbpedia.org/property/chemspiderid
|
17231095
|
| http://dbpedia.org/property/h
|
23
|
| http://dbpedia.org/property/iupacName
|
N,N-dimethyl-3-[oxy]propan-1-amine
|
| http://dbpedia.org/property/kegg
|
D10099
|
| http://dbpedia.org/property/legalStatus
|
Investigational
|
| http://dbpedia.org/property/n
|
3
|
| http://dbpedia.org/property/o
|
3
|
| http://dbpedia.org/property/pubchem
|
16071605
|
| http://dbpedia.org/property/s
|
1
|
| http://dbpedia.org/property/smiles
|
CNCCCOc4ccc3[nH]ncc3c4
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
NXQGEDVQXVTCDA-UHFFFAOYSA-N
|
| http://dbpedia.org/property/unii
|
EK40PJ0V49
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Antidementia +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Drugbox +
, http://dbpedia.org/resource/Template:Fdacite +
, http://dbpedia.org/resource/Template:Short_description +
, http://dbpedia.org/resource/Template:Keggcite +
, http://dbpedia.org/resource/Template:Serotonergics +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:Abandoned_drugs +
, http://dbpedia.org/resource/Category:Dimethylamino_compounds +
, http://dbpedia.org/resource/Category:1-Naphthyl_compounds +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Drug +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/Cerlapirdine?oldid=1120768438&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/Cerlapirdine.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/Cerlapirdine +
|
| owl:sameAs |
http://www.wikidata.org/entity/Q5064514 +
, http://fa.dbpedia.org/resource/%D8%B3%D8%B1%D9%84%D8%A7%D9%BE%DB%8C%D8%B1%D8%AF%DB%8C%D9%86 +
, http://rdf.freebase.com/ns/m.0hgps_x +
, http://dbpedia.org/resource/Cerlapirdine +
, http://sr.dbpedia.org/resource/Cerlapirdin +
, http://azb.dbpedia.org/resource/%D8%B3%D8%B1%D9%84%D8%A7%D9%BE%DB%8C%D8%B1%D8%AF%DB%8C%D9%86 +
, http://yago-knowledge.org/resource/Cerlapirdine +
, https://global.dbpedia.org/id/4hEsE +
, http://sh.dbpedia.org/resource/Cerlapirdin +
|
| rdf:type |
http://dbpedia.org/class/yago/PhysicalEntity100001930 +
, http://dbpedia.org/ontology/Drug +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
, http://dbpedia.org/class/yago/WikicatAmines +
, http://dbpedia.org/class/yago/MethaneSeries114951377 +
, http://dbpedia.org/class/yago/Amine114739004 +
, http://dbpedia.org/ontology/ChemicalSubstance +
, http://dbpedia.org/class/yago/Compound114818238 +
, http://dbpedia.org/class/yago/Chemical114806838 +
, http://dbpedia.org/class/yago/Substance100019613 +
, http://dbpedia.org/class/yago/Abstraction100002137 +
, http://www.wikidata.org/entity/Q8386 +
, http://dbpedia.org/class/yago/Matter100020827 +
, http://dbpedia.org/class/yago/OrganicCompound114727670 +
, http://dbpedia.org/class/yago/Material114580897 +
, http://dbpedia.org/class/yago/Relation100031921 +
, http://dbpedia.org/class/yago/Part113809207 +
, http://dbpedia.org/class/yago/AliphaticCompound114601294 +
|
| rdfs:comment |
Cerlapirdine (USAN; SAM-531, WAY-262,531, … Cerlapirdine (USAN; SAM-531, WAY-262,531, PF-05212365) is a drug which was under development by Wyeth/Pfizer for the treatment of cognitive disorders associated with Alzheimer's disease and schizophrenia. In a phase II clinical trial it demonstrated a trend toward efficacy along with a good side effect profile and no incidence of serious adverse events, but no further development has occurred since 2011. It exerts its effects by acting as a selective 5-HT6 receptor antagonist. as a selective 5-HT6 receptor antagonist.
|
| rdfs:label |
Cerlapirdine
|
