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, أبتازابين (بالإنجليزية: Aptazapine) ويعرف بالاسم التجاري أبتازابين (بالإنجليزية: Aptazapine) هو دواء لعلاج الاكتئاب.
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| rdfs:comment |
أبتازابين (بالإنجليزية: Aptazapine) ويعرف بالاسم التجاري أبتازابين (بالإنجليزية: Aptazapine) هو دواء لعلاج الاكتئاب.
, Aptazapine (developmental code name CGS-75 … Aptazapine (developmental code name CGS-7525A) is a tetracyclic antidepressant (TeCA) that was assayed in clinical trials for the treatment of depression in the 1980s but was never marketed. It is a potent α2-adrenergic receptor antagonist with ~10x the strength of the related compound mianserin and has also been shown to act as a 5-HT2 receptor antagonist and H1 receptor inverse agonist, while having no significant effects on the reuptake of serotonin or norepinephrine. Based on its pharmacological profile, aptazapine may be classified as a noradrenergic and specific serotonergic antidepressant (NaSSA).cific serotonergic antidepressant (NaSSA).
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| rdfs:label |
أبتازابين
, Aptazapine
|
