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Alamandine is a member of renin-angiotensi … Alamandine is a member of renin-angiotensin system (RAS) with cardiovascular functions that are protective and opposing to the classical axis. Alamandine is a product of ACE2-dependent catalytic hydrolysis of angiotensin A (Ang A) and can also be generated by decarboxylation of aspartic acid residue of Ang-(1-7). Ang A is Ala1-Ang II (alanine in place of aspartic acid). In mononuclear leucocytes, angiotensin II (Ang II) is converted to Ang A by decarboxylation of aspartic acid. Ang A is detected in human circulation and was shown to be higher in individuals with end-stage renal disease. individuals with end-stage renal disease.
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| http://dbpedia.org/ontology/alternativeName
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H-Ala-Arg-Val-Tyr-Ile-His-Pro-OH; L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline
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(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S) … (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acidyl)propanoyl]pyrrolidine-2-carboxylic acid
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H-Ala-Arg-Val-Tyr-Ile-His-Pro-OH; L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline
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| rdfs:comment |
Alamandine is a member of renin-angiotensi … Alamandine is a member of renin-angiotensin system (RAS) with cardiovascular functions that are protective and opposing to the classical axis. Alamandine is a product of ACE2-dependent catalytic hydrolysis of angiotensin A (Ang A) and can also be generated by decarboxylation of aspartic acid residue of Ang-(1-7). Ang A is Ala1-Ang II (alanine in place of aspartic acid). In mononuclear leucocytes, angiotensin II (Ang II) is converted to Ang A by decarboxylation of aspartic acid. Ang A is detected in human circulation and was shown to be higher in individuals with end-stage renal disease. individuals with end-stage renal disease.
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Alamandine
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