| http://dbpedia.org/ontology/abstract
|
AM-919 (part of the AM cannabinoid series) … AM-919 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid receptor agonist. It is a derivative of HU-210 which has been substituted with a 6β-(3-hydroxypropyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-919 represents a hybrid structure between the classical dibenzopyran and nonclassical cannabinoid families. AM-919 is somewhat less potent than HU-210 itself, but is still a potent agonist at both CB1 and CB2 with moderate selectivity for CB1, with a Ki of 2.2 nM at CB1 and 3.4 nM at CB2.h a Ki of 2.2 nM at CB1 and 3.4 nM at CB2.
|
| http://dbpedia.org/ontology/casNumber
|
164228-46-0
|
| http://dbpedia.org/ontology/chEMBL
|
121118
|
| http://dbpedia.org/ontology/fdaUniiCode
|
52KD6XK4KF
|
| http://dbpedia.org/ontology/pubchem
|
10741414
|
| http://dbpedia.org/ontology/thumbnail
|
http://commons.wikimedia.org/wiki/Special:FilePath/AM-919_Structure.svg?width=300 +
|
| http://dbpedia.org/ontology/wikiPageID
|
17361070
|
| http://dbpedia.org/ontology/wikiPageLength
|
3467
|
| http://dbpedia.org/ontology/wikiPageRevisionID
|
1099629770
|
| http://dbpedia.org/ontology/wikiPageWikiLink
|
http://dbpedia.org/resource/AM-4030 +
, http://dbpedia.org/resource/Cannabinoid_receptor_1 +
, http://dbpedia.org/resource/Category:Benzochromenes +
, http://dbpedia.org/resource/Cannabinoid +
, http://dbpedia.org/resource/Aliphatic +
, http://dbpedia.org/resource/List_of_AM_cannabinoids +
, http://dbpedia.org/resource/Category:AM_cannabinoids +
, http://dbpedia.org/resource/Hydroxyl +
, http://dbpedia.org/resource/Dissociation_constant +
, http://dbpedia.org/resource/Cannabinoid_receptor_agonist +
, http://dbpedia.org/resource/Cannabinoid_receptor_2 +
, http://dbpedia.org/resource/HU-210 +
, http://dbpedia.org/resource/Dibenzopyran +
, http://dbpedia.org/resource/Category:Primary_alcohols +
, http://dbpedia.org/resource/CP_cannabinoids +
, http://dbpedia.org/resource/Category:Phenols +
, http://dbpedia.org/resource/Analgesic +
|
| http://dbpedia.org/property/c
|
27
|
| http://dbpedia.org/property/casNumber
|
164228
|
| http://dbpedia.org/property/chembl
|
121118
|
| http://dbpedia.org/property/chemspiderid
|
8916745
|
| http://dbpedia.org/property/h
|
44
|
| http://dbpedia.org/property/iupacName
|
-9
|
| http://dbpedia.org/property/o
|
4
|
| http://dbpedia.org/property/pubchem
|
10741414
|
| http://dbpedia.org/property/smiles
|
OCCCC3C1CCCCC1c2cccCCCCCCC
|
| http://dbpedia.org/property/stdinchi
|
1
|
| http://dbpedia.org/property/stdinchikey
|
PHILDZBONNKMNU-UOTIDGTBSA-N
|
| http://dbpedia.org/property/unii
|
52
|
| http://dbpedia.org/property/verifiedrevid
|
477236033
|
| http://dbpedia.org/property/watchedfields
|
changed
|
| http://dbpedia.org/property/width
|
240
|
| http://dbpedia.org/property/wikiPageUsesTemplate
|
http://dbpedia.org/resource/Template:Short_description +
, http://dbpedia.org/resource/Template:Drugbox +
, http://dbpedia.org/resource/Template:Fdacite +
, http://dbpedia.org/resource/Template:Ebicite +
, http://dbpedia.org/resource/Template:Stdinchicite +
, http://dbpedia.org/resource/Template:Cascite +
, http://dbpedia.org/resource/Template:Chemspidercite +
, http://dbpedia.org/resource/Template:Reflist +
, http://dbpedia.org/resource/Template:Cannabinoid-stub +
, http://dbpedia.org/resource/Template:Cannabinoids +
|
| http://purl.org/dc/terms/subject
|
http://dbpedia.org/resource/Category:AM_cannabinoids +
, http://dbpedia.org/resource/Category:Benzochromenes +
, http://dbpedia.org/resource/Category:Primary_alcohols +
, http://dbpedia.org/resource/Category:Phenols +
|
| http://purl.org/linguistics/gold/hypernym
|
http://dbpedia.org/resource/Drug +
|
| http://www.w3.org/ns/prov#wasDerivedFrom
|
http://en.wikipedia.org/wiki/AM-919?oldid=1099629770&ns=0 +
|
| http://xmlns.com/foaf/0.1/depiction
|
http://commons.wikimedia.org/wiki/Special:FilePath/AM-919_Structure.svg +
|
| http://xmlns.com/foaf/0.1/isPrimaryTopicOf
|
http://en.wikipedia.org/wiki/AM-919 +
|
| owl:sameAs |
https://global.dbpedia.org/id/4JqLS +
, http://yago-knowledge.org/resource/AM-919 +
, http://sh.dbpedia.org/resource/AM-919 +
, http://www.wikidata.org/entity/Q4652507 +
, http://sr.dbpedia.org/resource/AM-919 +
, http://dbpedia.org/resource/AM-919 +
, http://rdf.freebase.com/ns/m.043qgc9 +
|
| rdf:type |
http://dbpedia.org/class/yago/WikicatAlcohols +
, http://umbel.org/umbel/rc/DrugProduct +
, http://dbpedia.org/class/yago/Matter100020827 +
, http://dbpedia.org/class/yago/Beverage107881800 +
, http://dbpedia.org/class/yago/OrganicCompound114727670 +
, http://dbpedia.org/class/yago/Material114580897 +
, http://dbpedia.org/class/yago/Compound114818238 +
, http://dbpedia.org/class/yago/Alcohol107884567 +
, http://www.wikidata.org/entity/Q8386 +
, http://dbpedia.org/class/yago/Liquid114940386 +
, http://dbpedia.org/class/yago/Chemical114806838 +
, http://dbpedia.org/class/yago/Substance100019613 +
, http://dbpedia.org/class/yago/Fluid114939900 +
, http://dbpedia.org/class/yago/Food100021265 +
, http://dbpedia.org/ontology/ChemicalSubstance +
, http://dbpedia.org/class/yago/Substance100020090 +
, http://dbpedia.org/ontology/Drug +
, http://dbpedia.org/class/yago/Agent114778436 +
, http://dbpedia.org/class/yago/DrugOfAbuse103248958 +
, http://dbpedia.org/class/yago/CausalAgent100007347 +
, http://dbpedia.org/class/yago/Drug103247620 +
, http://dbpedia.org/class/yago/Relation100031921 +
, http://dbpedia.org/class/yago/PhysicalEntity100001930 +
, http://dbpedia.org/class/yago/Part113809207 +
, http://dbpedia.org/class/yago/Abstraction100002137 +
, http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#ChemicalObject +
, http://dbpedia.org/class/yago/WikicatPhenols +
, http://dbpedia.org/class/yago/Phenol114989545 +
|
| rdfs:comment |
AM-919 (part of the AM cannabinoid series) … AM-919 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid receptor agonist. It is a derivative of HU-210 which has been substituted with a 6β-(3-hydroxypropyl) group. This adds a "southern" aliphatic hydroxyl group to the molecule as seen in the CP-series of nonclassical cannabinoid drugs, and so AM-919 represents a hybrid structure between the classical dibenzopyran and nonclassical cannabinoid families.ran and nonclassical cannabinoid families.
|
| rdfs:label |
AM-919
|
